Huber-Lang M - Search Results

1

Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis.

Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE. Skjeflo EW, et al. Crit Care. 2015 Nov 27;19:415. doi: 10.1186/s13054-015-1129-9. Crit Care. 2015. PMID: 26612199 Free PMC article.

2

Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis.

Flierl MA, Stahel PF, Rittirsch D, Huber-Lang M, Niederbichler AD, Hoesel LM, Touban BM, Morgan SJ, Smith WR, Ward PA, Ipaktchi K. Flierl MA, et al. Crit Care. 2009;13(1):R12. doi: 10.1186/cc7710. Epub 2009 Feb 6. Crit Care. 2009. PMID: 19196477 Free PMC article.

3

Bride and groom in systemic inflammation--the bells ring for complement and Toll in cooperation.

Barratt-Due A, Pischke SE, Brekke OL, Thorgersen EB, Nielsen EW, Espevik T, Huber-Lang M, Mollnes TE. Barratt-Due A, et al. Immunobiology. 2012 Nov;217(11):1047-56. doi: 10.1016/j.imbio.2012.07.019. Immunobiology. 2012. PMID: 22964230 Review.

4

Complement C3 and C5 deficiency affects fracture healing.

Ehrnthaller C, Huber-Lang M, Nilsson P, Bindl R, Redeker S, Recknagel S, Rapp A, Mollnes T, Amling M, Gebhard F, Ignatius A. Ehrnthaller C, et al. PLoS One. 2013 Nov 18;8(11):e81341. doi: 10.1371/journal.pone.0081341. eCollection 2013. PLoS One. 2013. PMID: 24260573 Free PMC article.

5

Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.

Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE. Huber-Lang M, et al. J Immunol. 2014 Jun 1;192(11):5324-31. doi: 10.4049/jimmunol.1400341. Epub 2014 Apr 30. J Immunol. 2014. PMID: 24790148 Free PMC article.

6

Complement in sepsis-when science meets clinics.

Mollnes TE, Huber-Lang M. Mollnes TE, et al. FEBS Lett. 2020 Aug;594(16):2621-2632. doi: 10.1002/1873-3468.13881. Epub 2020 Jul 21. FEBS Lett. 2020. PMID: 32621378 Free article. Review.

7

Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury.

Debler L, Palmer A, Braumüller S, Klohs B, Mollnes TE, Holzmann K, Huber-Lang M, Halbgebauer R. Debler L, et al. Mediators Inflamm. 2021 Jan 27;2021:6654318. doi: 10.1155/2021/6654318. eCollection 2021. Mediators Inflamm. 2021. PMID: 33574730 Free PMC article.

8

A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity.

Nilsson PH, Johnson C, Quach QH, Macpherson A, Durrant O, Pischke SE, Fure H, Landsem A, Bergseth G, Schjalm C, Haugaard-Kedström LM, Huber-Lang M, van den Elsen J, Brekke OL, Mollnes TE. Nilsson PH, et al. J Immunol. 2021 Sep 15;207(6):1641-1651. doi: 10.4049/jimmunol.2001471. Epub 2021 Aug 11. J Immunol. 2021. PMID: 34380648 Free PMC article.

9

Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma.

Lupu L, Horst K, Greven J, Mert Ü, Ludviksen JAK, Pettersen K, Lau C, Li Y, Palmer A, Qin K, Zhang X, Mayer B, van Griensven M, Huber-Lang M, Hildebrand F, Mollnes TE. Lupu L, et al. Front Immunol. 2022 Aug 18;13:952267. doi: 10.3389/fimmu.2022.952267. eCollection 2022. Front Immunol. 2022. PMID: 36059503 Free PMC article.

10

Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes.

Roos J, Zinngrebe J, Huber-Lang M, Lupu L, Schmidt MA, Strobel H, Westhoff MA, Stifel U, Gebhard F, Wabitsch M, Mollnes TE, Debatin KM, Halbgebauer R, Fischer-Posovszky P. Roos J, et al. Among authors: huber lang m. Cell Death Dis. 2024 Apr 23;15(4):285. doi: 10.1038/s41419-024-06676-9. Cell Death Dis. 2024. PMID: 38653969 Free PMC article.

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