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Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
Riemenschneider H, Guo Q, Bader J, Frottin F, Farny D, Kleinberger G, Haass C, Mann M, Hartl FU, Baumeister W, Hipp MS, Meissner F, Fernández-Busnadiego R, Edbauer D. Riemenschneider H, et al. Among authors: frottin f. EMBO Rep. 2022 Jun 7;23(6):e53890. doi: 10.15252/embr.202153890. Epub 2022 Apr 19. EMBO Rep. 2022. PMID: 35438230 Free PMC article.
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Khosravi B, LaClair KD, Riemenschneider H, Zhou Q, Frottin F, Mareljic N, Czuppa M, Farny D, Hartmann H, Michaelsen M, Arzberger T, Hartl FU, Hipp MS, Edbauer D. Khosravi B, et al. Among authors: frottin f. EMBO J. 2020 Apr 15;39(8):e102811. doi: 10.15252/embj.2019102811. Epub 2020 Mar 16. EMBO J. 2020. PMID: 32175624 Free PMC article.
In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Guo Q, Lehmer C, Martínez-Sánchez A, Rudack T, Beck F, Hartmann H, Pérez-Berlanga M, Frottin F, Hipp MS, Hartl FU, Edbauer D, Baumeister W, Fernández-Busnadiego R. Guo Q, et al. Among authors: frottin f. Cell. 2018 Feb 8;172(4):696-705.e12. doi: 10.1016/j.cell.2017.12.030. Epub 2018 Feb 1. Cell. 2018. PMID: 29398115 Free PMC article.
The proteomics of N-terminal methionine cleavage.
Frottin F, Martinez A, Peynot P, Mitra S, Holz RC, Giglione C, Meinnel T. Frottin F, et al. Mol Cell Proteomics. 2006 Dec;5(12):2336-49. doi: 10.1074/mcp.M600225-MCP200. Epub 2006 Sep 8. Mol Cell Proteomics. 2006. PMID: 16963780 Free article.
13 results