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7 results
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A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma.
Cancer Chemother Pharmacol. 2021 Jan;87(1):135-144. doi: 10.1007/s00280-020-04201-1. Epub 2020 Nov 19.
Cancer Chemother Pharmacol. 2021.
PMID: 33215270
Free PMC article.
Clinical Trial.
Phase 1 study of PSMA ADC, an antibody-drug conjugate targeting prostate-specific membrane antigen, in chemotherapy-refractory prostate cancer.
Petrylak DP, Kantoff P, Vogelzang NJ, Mega A, Fleming MT, Stephenson JJ Jr, Frank R, Shore ND, Dreicer R, McClay EF, Berry WR, Agarwal M, DiPippo VA, Rotshteyn Y, Stambler N, Olson WC, Morris SA, Israel RJ.
Petrylak DP, et al. Among authors: stephenson jj jr.
Prostate. 2019 May;79(6):604-613. doi: 10.1002/pros.23765. Epub 2019 Jan 20.
Prostate. 2019.
PMID: 30663074
Clinical Trial.
Item in Clipboard
A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer.
Adjei AA, Richards DA, El-Khoueiry A, Braiteh F, Becerra CH, Stephenson JJ Jr, Hezel AF, Sherman M, Garbo L, Leffingwell DP, Iverson C, Miner JN, Shen Z, Yeh LT, Gunawan S, Wilson DM, Manhard KJ, Rajagopalan P, Krissel H, Clendeninn NJ.
Adjei AA, et al. Among authors: stephenson jj jr.
Clin Cancer Res. 2016 May 15;22(10):2368-76. doi: 10.1158/1078-0432.CCR-15-1681. Epub 2015 Dec 7.
Clin Cancer Res. 2016.
PMID: 26644411
Free PMC article.
Clinical Trial.
Item in Clipboard
The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors.
Rosen LS, Lipton L, Price TJ, Belman ND, Boccia RV, Hurwitz HI, Stephenson JJ Jr, Wirth LJ, McCoy S, Hei YJ, Hsu CP, Tebbutt NC.
Rosen LS, et al. Among authors: stephenson jj jr.
BMC Cancer. 2013 May 16;13:242. doi: 10.1186/1471-2407-13-242.
BMC Cancer. 2013.
PMID: 23679351
Free PMC article.
Clinical Trial.
Item in Clipboard
A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer.
Kindler HL, Richards DA, Garbo LE, Garon EB, Stephenson JJ Jr, Rocha-Lima CM, Safran H, Chan D, Kocs DM, Galimi F, McGreivy J, Bray SL, Hei Y, Feigal EG, Loh E, Fuchs CS.
Kindler HL, et al. Among authors: stephenson jj jr.
Ann Oncol. 2012 Nov;23(11):2834-2842. doi: 10.1093/annonc/mds142. Epub 2012 Jun 13.
Ann Oncol. 2012.
PMID: 22700995
Free article.
Clinical Trial.
Item in Clipboard
Phase 1 dose-escalation trial of tremelimumab plus sunitinib in patients with metastatic renal cell carcinoma.
Rini BI, Stein M, Shannon P, Eddy S, Tyler A, Stephenson JJ Jr, Catlett L, Huang B, Healey D, Gordon M.
Rini BI, et al. Among authors: stephenson jj jr.
Cancer. 2011 Feb 15;117(4):758-67. doi: 10.1002/cncr.25639. Epub 2010 Oct 4.
Cancer. 2011.
PMID: 20922784
Free article.
Clinical Trial.
Item in Clipboard
Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers.
Von Hoff DD, Stephenson JJ Jr, Rosen P, Loesch DM, Borad MJ, Anthony S, Jameson G, Brown S, Cantafio N, Richards DA, Fitch TR, Wasserman E, Fernandez C, Green S, Sutherland W, Bittner M, Alarcon A, Mallery D, Penny R.
Von Hoff DD, et al. Among authors: stephenson jj jr.
J Clin Oncol. 2010 Nov 20;28(33):4877-83. doi: 10.1200/JCO.2009.26.5983. Epub 2010 Oct 4.
J Clin Oncol. 2010.
PMID: 20921468
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