Nefzi A - Search Results

1

Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.

Houghten RA, Ganno ML, McLaughlin JP, Dooley CT, Eans SO, Santos RG, LaVoi T, Nefzi A, Welmaker G, Giulianotti MA, Toll L. Houghten RA, et al. Among authors: nefzi a. ACS Comb Sci. 2016 Jan 11;18(1):51-64. doi: 10.1021/acscombsci.5b00126. Epub 2016 Jan 5. ACS Comb Sci. 2016. PMID: 26651386 Free PMC article.

2

Combinatorial chemistry: from peptides and peptidomimetics to small organic and heterocyclic compounds.

Nefzi A, Dooley C, Ostresh JM, Houghten RA. Nefzi A, et al. Bioorg Med Chem Lett. 1998 Sep 8;8(17):2273-8. doi: 10.1016/s0960-894x(98)00412-0. Bioorg Med Chem Lett. 1998. PMID: 9873527

3

Mixture-based synthetic combinatorial libraries.

Houghten RA, Pinilla C, Appel JR, Blondelle SE, Dooley CT, Eichler J, Nefzi A, Ostresh JM. Houghten RA, et al. Among authors: nefzi a. J Med Chem. 1999 Sep 23;42(19):3743-78. doi: 10.1021/jm990174v. J Med Chem. 1999. PMID: 10508425 Review. No abstract available.

4

Solid-phase synthesis of bis-2-imidazolidinethiones from resin-bound tripeptides.

Nefzi A, Giulianotti MA, Ong NA, Houghten RA. Nefzi A, et al. Org Lett. 2000 Oct 19;2(21):3349-50. doi: 10.1021/ol000225e. Org Lett. 2000. PMID: 11029207

5

Solid-phase synthesis of bis-heterocyclic compounds from resin-bound orthogonally protected lysine.

Nefzi A, Giulianotti MA, Houghten RA. Nefzi A, et al. J Comb Chem. 2001 Jan-Feb;3(1):68-70. doi: 10.1021/cc000061t. J Comb Chem. 2001. PMID: 11148065

6

Tethered libraries: solid-phase synthesis of substituted urea-linked bicyclic guanidines.

Acharya AN, Nefzi A, Ostresh JM, Houghten RA. Acharya AN, et al. Among authors: nefzi a. J Comb Chem. 2001 Mar-Apr;3(2):189-95. doi: 10.1021/cc0000803. J Comb Chem. 2001. PMID: 11300860

7

Solid-phase synthesis of alpha,alpha-difluoro-beta-amino acids via the Reformatsky reaction.

Vidal A, Nefzi A, Houghten RA. Vidal A, et al. Among authors: nefzi a. J Org Chem. 2001 Nov 30;66(24):8268-72. doi: 10.1021/jo010872z. J Org Chem. 2001. PMID: 11722240 No abstract available.

8

Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides.

Nefzi A, Ostresh JM, Houghten RA. Nefzi A, et al. Biopolymers. 2001;60(3):212-9. doi: 10.1002/1097-0282(2001)60:3<212::AID-BIP10033>3.0.CO;2-D. Biopolymers. 2001. PMID: 11774227 Review.

9

The Current Status of Heterocyclic Combinatorial Libraries.

Nefzi A, Ostresh JM, Houghten RA. Nefzi A, et al. Chem Rev. 1997 Apr 1;97(2):449-472. doi: 10.1021/cr960010b. Chem Rev. 1997. PMID: 11848878 No abstract available.

10

Solid-phase synthesis of linear ureas tethered to hydantoins and thiohydantoins.

Nefzi A, Giulianotti M, Truong L, Rattan S, Ostresh JM, Houghten RA. Nefzi A, et al. J Comb Chem. 2002 Mar-Apr;4(2):175-8. doi: 10.1021/cc010064l. J Comb Chem. 2002. PMID: 11886293

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