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Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.
Duffy DJ, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, Mehta JP, Killick K, Whilde J, Turriziani B, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W. Duffy DJ, et al. Among authors: whilde j. Oncotarget. 2015 Dec 22;6(41):43182-201. doi: 10.18632/oncotarget.6568. Oncotarget. 2015. PMID: 26673823 Free PMC article.
Wnt signalling is a bi-directional vulnerability of cancer cells.
Duffy DJ, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, Haley B, Whilde J, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W. Duffy DJ, et al. Among authors: whilde j. Oncotarget. 2016 Sep 13;7(37):60310-60331. doi: 10.18632/oncotarget.11203. Oncotarget. 2016. PMID: 27531891 Free PMC article.
Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors.
Yetsko K, Farrell JA, Blackburn NB, Whitmore L, Stammnitz MR, Whilde J, Eastman CB, Ramia DR, Thomas R, Krstic A, Linser P, Creer S, Carvalho G, Devlin MA, Nahvi N, Leandro AC, deMaar TW, Burkhalter B, Murchison EP, Schnitzler C, Duffy DJ. Yetsko K, et al. Among authors: whilde j. Commun Biol. 2021 Feb 1;4(1):152. doi: 10.1038/s42003-021-01656-7. Commun Biol. 2021. PMID: 33526843 Free PMC article.