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A highly sensitive and selective LC-MS/MS method to quantify asunaprevir, an HCV NS3 protease inhibitor, in human plasma in support of pharmacokinetic studies.
Kandoussi H, Jiang H, Zeng J, Zheng N, Kadiyala P, Eley T, He B, Garimella T, Demers R, Cojocaru L, Aubry AF, Arnold ME. Kandoussi H, et al. Among authors: cojocaru l. J Pharm Biomed Anal. 2016 Feb 5;119:145-51. doi: 10.1016/j.jpba.2015.11.028. Epub 2015 Nov 23. J Pharm Biomed Anal. 2016. PMID: 26683987
Sensitive and accurate liquid chromatography-tandem mass spectrometry methods for quantitative determination of a novel hepatitis C NS5B inhibitor BMS-791325 and its active metabolite in human plasma and urine.
Jiang H, Demers R, Kandoussi H, Burrell R, Eley T, Kadiyala P, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME, Zeng J. Jiang H, et al. Among authors: cojocaru l. J Pharm Biomed Anal. 2015 Mar 25;107:17-23. doi: 10.1016/j.jpba.2014.12.011. Epub 2014 Dec 17. J Pharm Biomed Anal. 2015. PMID: 25562845
Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma.
Jiang H, Kandoussi H, Zeng J, Wang J, Demers R, Eley T, He B, Burrell R, Easter J, Kadiyala P, Pursley J, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME. Jiang H, et al. Among authors: cojocaru l. J Pharm Biomed Anal. 2015 Mar 25;107:409-18. doi: 10.1016/j.jpba.2015.01.027. Epub 2015 Jan 20. J Pharm Biomed Anal. 2015. PMID: 25676854
A sensitive and accurate liquid chromatography-tandem mass spectrometry method for quantitative determination of the novel hepatitis C NS5A inhibitor BMS-790052 (daclastasvir) in human plasma and urine.
Jiang H, Zeng J, Kandoussi H, Liu Y, Wang X, Bifano M, Cojocaru L, Ryan J, Arnold ME. Jiang H, et al. Among authors: cojocaru l. J Chromatogr A. 2012 Jul 6;1245:117-21. doi: 10.1016/j.chroma.2012.05.028. Epub 2012 May 14. J Chromatogr A. 2012. PMID: 22640838
Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: method validation and overcoming specific and non-specific binding at low concentrations.
Xu XS, Demers R, Gu H, Christopher LJ, Su H, Cojocaru L, Boulton DW, Kirby M, Stouffer B, Humphreys WG, Arnold ME. Xu XS, et al. Among authors: cojocaru l. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 15;889-890:77-86. doi: 10.1016/j.jchromb.2012.01.033. Epub 2012 Feb 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22349123
2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 2 - hybrid LBA/LCMS, ELN & regulatory agencies' input).
Dufield D, Neubert H, Garofolo F, Kirkovsky L, Stevenson L, Dumont I, Kaur S, Xu K, Alley SC, Szapacs M, Arnold M, Bansal S, Haidar S, Welink J, Le Blaye O, Wakelin-Smith J, Whale E, Ishii-Watabe A, Bustard M, Katori N, Amaravadi L, Aubry AF, Beaver C, Bergeron A, Cai XY, Cojocaru L, DeSilva B, Duggan J, Fluhler E, Gorovits B, Gupta S, Hayes R, Ho S, Ingelse B, King L, Lévesque A, Lowes S, Ma M, Musuku A, Myler H, Olah T, Patel S, Rose M, Schultz G, Smeraglia J, Swanson S, Torri A, Vazvaei F, Wilson A, Woolf E, Xue L, Yang TY. Dufield D, et al. Among authors: cojocaru l. Bioanalysis. 2014;6(23):3237-49. doi: 10.4155/bio.14.279. Bioanalysis. 2014. PMID: 25529890
71 results