Osorio FG - Search Results

1

Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.

Osorio FG, Soria-Valles C, Santiago-Fernández O, Bernal T, Mittelbrunn M, Colado E, Rodríguez F, Bonzon-Kulichenko E, Vázquez J, Porta-de-la-Riva M, Cerón J, Fueyo A, Li J, Green AR, Freije JM, López-Otín C. Osorio FG, et al. Nat Med. 2016 Jan;22(1):91-6. doi: 10.1038/nm.4013. Epub 2015 Dec 21. Nat Med. 2016. PMID: 26692333

2

The novel tumor suppressor AIRAPL regulates IGF1R proteostasis.

Osorio FG, Freije JM, López-Otín C. Osorio FG, et al. Cell Cycle. 2016;15(7):873-4. doi: 10.1080/15384101.2016.1151725. Epub 2016 Feb 22. Cell Cycle. 2016. PMID: 26901531 Free PMC article. No abstract available.

3

Proteostasis alterations in myeloproliferative neoplasms: Oncogenic relevance and therapeutic opportunities.

Santiago-Fernández O, Osorio FG, López-Otín C. Santiago-Fernández O, et al. Among authors: osorio fg. Exp Hematol. 2016 Jul;44(7):574-7. doi: 10.1016/j.exphem.2016.04.004. Epub 2016 Apr 14. Exp Hematol. 2016. PMID: 27090962 Free article. Review.

4

Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome.

Santiago-Fernández O, Osorio FG, Quesada V, Rodríguez F, Basso S, Maeso D, Rolas L, Barkaway A, Nourshargh S, Folgueras AR, Freije JMP, López-Otín C. Santiago-Fernández O, et al. Among authors: osorio fg. Nat Med. 2019 Mar;25(3):423-426. doi: 10.1038/s41591-018-0338-6. Epub 2019 Feb 18. Nat Med. 2019. PMID: 30778239 Free PMC article.

5

NF-κB signaling as a driver of ageing.

Osorio FG, Soria-Valles C, Santiago-Fernández O, Freije JM, López-Otín C. Osorio FG, et al. Int Rev Cell Mol Biol. 2016;326:133-74. doi: 10.1016/bs.ircmb.2016.04.003. Epub 2016 May 30. Int Rev Cell Mol Biol. 2016. PMID: 27572128 Review.

6

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Varela I, Pereira S, Ugalde AP, Navarro CL, Suárez MF, Cau P, Cadiñanos J, Osorio FG, Foray N, Cobo J, de Carlos F, Lévy N, Freije JM, López-Otín C. Varela I, et al. Among authors: osorio fg. Nat Med. 2008 Jul;14(7):767-72. doi: 10.1038/nm1786. Epub 2008 Jun 29. Nat Med. 2008. PMID: 18587406

7

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.

Mariño G, Ugalde AP, Fernández AF, Osorio FG, Fueyo A, Freije JM, López-Otín C. Mariño G, et al. Among authors: osorio fg. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16268-73. doi: 10.1073/pnas.1002696107. Epub 2010 Aug 30. Proc Natl Acad Sci U S A. 2010. PMID: 20805469 Free PMC article.

8

Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response.

Osorio FG, Bárcena C, Soria-Valles C, Ramsay AJ, de Carlos F, Cobo J, Fueyo A, Freije JM, López-Otín C. Osorio FG, et al. Genes Dev. 2012 Oct 15;26(20):2311-24. doi: 10.1101/gad.197954.112. Epub 2012 Sep 26. Genes Dev. 2012. PMID: 23019125 Free PMC article.

9

NF-kB in premature aging.

Osorio FG, López-Otín C, Freije JM. Osorio FG, et al. Aging (Albany NY). 2012 Nov;4(11):726-7. doi: 10.18632/aging.100502. Aging (Albany NY). 2012. PMID: 23211391 Free PMC article. Review. No abstract available.

10

NF-κB activation impairs somatic cell reprogramming in ageing.

Soria-Valles C, Osorio FG, Gutiérrez-Fernández A, De Los Angeles A, Bueno C, Menéndez P, Martín-Subero JI, Daley GQ, Freije JM, López-Otín C. Soria-Valles C, et al. Among authors: osorio fg. Nat Cell Biol. 2015 Aug;17(8):1004-13. doi: 10.1038/ncb3207. Epub 2015 Jul 27. Nat Cell Biol. 2015. PMID: 26214134 Retracted.

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