McIntosh K - Search Results

1

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology.

Huesa C, Ortiz AC, Dunning L, McGavin L, Bennett L, McIntosh K, Crilly A, Kurowska-Stolarska M, Plevin R, van 't Hof RJ, Rowan AD, McInnes IB, Goodyear CS, Lockhart JC, Ferrell WR. Huesa C, et al. Among authors: mcintosh k. Ann Rheum Dis. 2016 Nov;75(11):1989-1997. doi: 10.1136/annrheumdis-2015-208268. Epub 2015 Dec 23. Ann Rheum Dis. 2016. PMID: 26698846 Free PMC article.

2

The therapeutic potential of proteinase-activated receptors in arthritis.

McIntosh KA, Plevin R, Ferrell WR, Lockhart JC. McIntosh KA, et al. Curr Opin Pharmacol. 2007 Jun;7(3):334-8. doi: 10.1016/j.coph.2007.01.002. Epub 2007 Mar 21. Curr Opin Pharmacol. 2007. PMID: 17369094 Review.

3

Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs.

McIntosh K, Cunningham MR, Cadalbert L, Lockhart J, Boyd G, Ferrell WR, Plevin R. McIntosh K, et al. Cell Signal. 2010 Feb;22(2):265-73. doi: 10.1016/j.cellsig.2009.09.028. Epub 2009 Sep 23. Cell Signal. 2010. PMID: 19781631 Free PMC article.

4

Inhibitory kappa B Kinases as targets for pharmacological regulation.

Gamble C, McIntosh K, Scott R, Ho KH, Plevin R, Paul A. Gamble C, et al. Among authors: mcintosh k. Br J Pharmacol. 2012 Feb;165(4):802-19. doi: 10.1111/j.1476-5381.2011.01608.x. Br J Pharmacol. 2012. PMID: 21797846 Free PMC article. Review.

5

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).

Cunningham MR, McIntosh KA, Pediani JD, Robben J, Cooke AE, Nilsson M, Gould GW, Mundell S, Milligan G, Plevin R. Cunningham MR, et al. J Biol Chem. 2012 May 11;287(20):16656-69. doi: 10.1074/jbc.M111.315911. Epub 2012 Mar 12. J Biol Chem. 2012. PMID: 22411985 Free PMC article.

6

Protease-Activated Receptor 2: Are Common Functions in Glial and Immune Cells Linked to Inflammation-Related CNS Disorders?

Bushell TJ, Cunningham MR, McIntosh KA, Moudio S, Plevin R. Bushell TJ, et al. Curr Drug Targets. 2016;17(16):1861-1870. doi: 10.2174/1389450117666151209115232. Curr Drug Targets. 2016. PMID: 26648078 Free article. Review.

7

Proteinase-activated receptors (PARs) as targets for antiplatelet therapy.

Cunningham M, McIntosh K, Bushell T, Sloan G, Plevin R. Cunningham M, et al. Among authors: mcintosh k. Biochem Soc Trans. 2016 Apr 15;44(2):606-12. doi: 10.1042/BST20150282. Biochem Soc Trans. 2016. PMID: 27068977 Free article. Review.

8

Inhibition of cytokine-mediated JNK signalling by purinergic P2Y₁₁ receptors, a novel protective mechanism in endothelial cells.

Ng PY, McIntosh KA, Hargrave G, Ho KH, Paul A, Plevin R. Ng PY, et al. Cell Signal. 2018 Nov;51:59-71. doi: 10.1016/j.cellsig.2018.07.016. Epub 2018 Aug 2. Cell Signal. 2018. PMID: 30076967 Free article.

9

Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis.

Schroeder J, Ross K, McIntosh K, Jabber S, Woods S, Crowe J, Patterson Kane J, Alexander J, Lawrence C, Plevin R. Schroeder J, et al. Among authors: mcintosh k. RMD Open. 2019 Jan 11;5(1):e000711. doi: 10.1136/rmdopen-2018-000711. eCollection 2019. RMD Open. 2019. PMID: 30713718 Free PMC article.

10

The development of proteinase-activated receptor-2 modulators and the challenges involved.

McIntosh KA, Cunningham MR, Bushell T, Plevin R. McIntosh KA, et al. Biochem Soc Trans. 2020 Dec 18;48(6):2525-2537. doi: 10.1042/BST20200191. Biochem Soc Trans. 2020. PMID: 33242065 Free PMC article. Review.

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