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Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation.
Mazzola MA, Raheja R, Murugaiyan G, Rajabi H, Kumar D, Pertel T, Regev K, Griffin R, Aly L, Kivisakk P, Nejad P, Patel B, Gwanyalla N, Hei H, Glanz B, Chitnis T, Weiner HL, Gandhi R. Mazzola MA, et al. Among authors: pertel t. J Neuroinflammation. 2015 Dec 30;12:245. doi: 10.1186/s12974-015-0460-z. J Neuroinflammation. 2015. PMID: 26714756 Free PMC article.
A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity.
Esposito F, Sorosina M, Ottoboni L, Lim ET, Replogle JM, Raj T, Brambilla P, Liberatore G, Guaschino C, Romeo M, Pertel T, Stankiewicz JM, Martinelli V, Rodegher M, Weiner HL, Brassat D, Benoist C, Patsopoulos NA, Comi G, Elyaman W, Martinelli Boneschi F, De Jager PL. Esposito F, et al. Among authors: pertel t. Ann Neurol. 2015 Jul;78(1):115-27. doi: 10.1002/ana.24429. Epub 2015 May 14. Ann Neurol. 2015. PMID: 25914168
Reactivation of latent HIV-1 by inhibition of BRD4.
Zhu J, Gaiha GD, John SP, Pertel T, Chin CR, Gao G, Qu H, Walker BD, Elledge SJ, Brass AL. Zhu J, et al. Among authors: pertel t. Cell Rep. 2012 Oct 25;2(4):807-16. doi: 10.1016/j.celrep.2012.09.008. Epub 2012 Oct 4. Cell Rep. 2012. PMID: 23041316 Free PMC article.
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome.
Soghoian DZ, Jessen H, Flanders M, Sierra-Davidson K, Cutler S, Pertel T, Ranasinghe S, Lindqvist M, Davis I, Lane K, Rychert J, Rosenberg ES, Piechocka-Trocha A, Brass AL, Brenchley JM, Walker BD, Streeck H. Soghoian DZ, et al. Among authors: pertel t. Sci Transl Med. 2012 Feb 29;4(123):123ra25. doi: 10.1126/scitranslmed.3003165. Sci Transl Med. 2012. PMID: 22378925 Free PMC article.
Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.
Garcia-Beltran WF, Hölzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, Altfeld M. Garcia-Beltran WF, et al. Among authors: pertel t. Nat Immunol. 2016 Sep;17(9):1067-74. doi: 10.1038/ni.3513. Epub 2016 Jul 25. Nat Immunol. 2016. PMID: 27455421 Free PMC article.
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Huang YH, et al. Among authors: pertel t. Nature. 2015 Jan 15;517(7534):386-90. doi: 10.1038/nature13848. Epub 2014 Oct 26. Nature. 2015. PMID: 25363763 Free PMC article.
Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy.
Sabatos-Peyton CA, Nevin J, Brock A, Venable JD, Tan DJ, Kassam N, Xu F, Taraszka J, Wesemann L, Pertel T, Acharya N, Klapholz M, Etminan Y, Jiang X, Huang YH, Blumberg RS, Kuchroo VK, Anderson AC. Sabatos-Peyton CA, et al. Among authors: pertel t. Oncoimmunology. 2017 Nov 9;7(2):e1385690. doi: 10.1080/2162402X.2017.1385690. eCollection 2018. Oncoimmunology. 2017. PMID: 29308307 Free PMC article.
Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Huang YH, et al. Among authors: pertel t. Nature. 2016 Aug 18;536(7616):359. doi: 10.1038/nature17421. Epub 2016 Mar 16. Nature. 2016. PMID: 26982724 Free PMC article. No abstract available.
45 results