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Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Johnson CE, Huang YY, Parrish AB, Smith MI, Vaughn AE, Zhang Q, Wright KM, Van Dyke T, Wechsler-Reya RJ, Kornbluth S, Deshmukh M. Johnson CE, et al. Among authors: deshmukh m. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20820-5. doi: 10.1073/pnas.0709101105. Epub 2007 Dec 18. Proc Natl Acad Sci U S A. 2007. PMID: 18093951 Free PMC article.
Mature neurons: equipped for survival.
Kole AJ, Annis RP, Deshmukh M. Kole AJ, et al. Among authors: deshmukh m. Cell Death Dis. 2013 Jun 27;4(6):e689. doi: 10.1038/cddis.2013.220. Cell Death Dis. 2013. PMID: 23807218 Free PMC article. Review.
Adenosine: essential for life but licensed to kill.
Gama V, Deshmukh M. Gama V, et al. Among authors: deshmukh m. Mol Cell. 2013 May 9;50(3):307-8. doi: 10.1016/j.molcel.2013.04.020. Mol Cell. 2013. PMID: 23664374 Free PMC article.
Apoptotic cell death regulation in neurons.
Hollville E, Romero SE, Deshmukh M. Hollville E, et al. Among authors: deshmukh m. FEBS J. 2019 Sep;286(17):3276-3298. doi: 10.1111/febs.14970. Epub 2019 Jul 12. FEBS J. 2019. PMID: 31230407 Free PMC article. Review.
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM. Connolly NMC, et al. Among authors: deshmukh m. Cell Death Differ. 2018 Mar;25(3):542-572. doi: 10.1038/s41418-017-0020-4. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229998 Free PMC article. Review.
461 results