Ursini-Siegel J - Search Results

1

STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis.

Jones LM, Broz ML, Ranger JJ, Ozcelik J, Ahn R, Zuo D, Ursini-Siegel J, Hallett MT, Krummel M, Muller WJ. Jones LM, et al. Cancer Res. 2016 Mar 15;76(6):1416-28. doi: 10.1158/0008-5472.CAN-15-2770. Epub 2015 Dec 30. Cancer Res. 2016. PMID: 26719528 Free PMC article.

2

Insights from transgenic mouse models of ERBB2-induced breast cancer.

Ursini-Siegel J, Schade B, Cardiff RD, Muller WJ. Ursini-Siegel J, et al. Nat Rev Cancer. 2007 May;7(5):389-97. doi: 10.1038/nrc2127. Epub 2007 Apr 19. Nat Rev Cancer. 2007. PMID: 17446858 Review.

3

Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development.

Ursini-Siegel J, Rajput AB, Lu H, Sanguin-Gendreau V, Zuo D, Papavasiliou V, Lavoie C, Turpin J, Cianflone K, Huntsman DG, Muller WJ. Ursini-Siegel J, et al. Mol Cell Biol. 2007 Sep;27(18):6361-71. doi: 10.1128/MCB.00686-07. Epub 2007 Jul 16. Mol Cell Biol. 2007. PMID: 17636013 Free PMC article.

4

ShcA signalling is essential for tumour progression in mouse models of human breast cancer.

Ursini-Siegel J, Hardy WR, Zuo D, Lam SH, Sanguin-Gendreau V, Cardiff RD, Pawson T, Muller WJ. Ursini-Siegel J, et al. EMBO J. 2008 Mar 19;27(6):910-20. doi: 10.1038/emboj.2008.22. Epub 2008 Feb 14. EMBO J. 2008. PMID: 18273058 Free PMC article.

5

The ShcA adaptor protein is a critical regulator of breast cancer progression.

Ursini-Siegel J, Muller WJ. Ursini-Siegel J, et al. Cell Cycle. 2008 Jul 1;7(13):1936-43. doi: 10.4161/cc.7.13.6205. Epub 2008 Apr 24. Cell Cycle. 2008. PMID: 18604176 Review.

6

Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.

Ursini-Siegel J, Cory S, Zuo D, Hardy WR, Rexhepaj E, Lam S, Schade B, Jirstrom K, Bjur E, Piccirillo CA, Denardo D, Coussens LM, Brennan DJ, Gallagher WM, Park M, Pawson T, Hallett M, Muller WJ. Ursini-Siegel J, et al. Cancer Res. 2010 Oct 15;70(20):7776-87. doi: 10.1158/0008-5472.CAN-10-2229. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924104 Free PMC article.

7

The ShcA SH2 domain engages a 14-3-3/PI3'K signaling complex and promotes breast cancer cell survival.

Ursini-Siegel J, Hardy WR, Zheng Y, Ling C, Zuo D, Zhang C, Podmore L, Pawson T, Muller WJ. Ursini-Siegel J, et al. Oncogene. 2012 Nov 29;31(48):5038-44. doi: 10.1038/onc.2012.4. Epub 2012 Jan 30. Oncogene. 2012. PMID: 22286768

8

The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.

Ahn R, Sabourin V, Ha JR, Cory S, Maric G, Im YK, Hardy WR, Zhao H, Park M, Hallett M, Siegel PM, Pawson T, Ursini-Siegel J. Ahn R, et al. Cancer Res. 2013 Jul 15;73(14):4521-32. doi: 10.1158/0008-5472.CAN-12-4178. Epub 2013 May 21. Cancer Res. 2013. PMID: 23695548

9

Peripheral blood cells inform on the presence of breast cancer: a population-based case-control study.

Dumeaux V, Ursini-Siegel J, Flatberg A, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Lund E. Dumeaux V, et al. Int J Cancer. 2015 Feb 1;136(3):656-67. doi: 10.1002/ijc.29030. Epub 2014 Jun 25. Int J Cancer. 2015. PMID: 24931809 Free PMC article.

10

p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.

Hudson J, Ha JR, Sabourin V, Ahn R, La Selva R, Livingstone J, Podmore L, Knight J, Forrest L, Beauchemin N, Hallett M, Park M, Ursini-Siegel J. Hudson J, et al. Mol Cell Biol. 2014 Oct 1;34(19):3689-701. doi: 10.1128/MCB.00341-14. Epub 2014 Jul 28. Mol Cell Biol. 2014. PMID: 25071152 Free PMC article.

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