Ottenhoff TH - Search Results

1

Approaching a diagnostic point-of-care test for pediatric tuberculosis through evaluation of immune biomarkers across the clinical disease spectrum.

Jenum S, Dhanasekaran S, Lodha R, Mukherjee A, Kumar Saini D, Singh S, Singh V, Medigeshi G, Haks MC, Ottenhoff TH, Doherty TM, Kabra SK, Ritz C, Grewal HM. Jenum S, et al. Among authors: ottenhoff th. Sci Rep. 2016 Jan 4;6:18520. doi: 10.1038/srep18520. Sci Rep. 2016. PMID: 26725873 Free PMC article.

2

Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers.

van Dissel JT, Arend SM, Prins C, Bang P, Tingskov PN, Lingnau K, Nouta J, Klein MR, Rosenkrands I, Ottenhoff TH, Kromann I, Doherty TM, Andersen P. van Dissel JT, et al. Among authors: ottenhoff th. Vaccine. 2010 Apr 30;28(20):3571-81. doi: 10.1016/j.vaccine.2010.02.094. Epub 2010 Mar 11. Vaccine. 2010. PMID: 20226890 Clinical Trial.

3

First in humans: a new molecularly defined vaccine shows excellent safety and strong induction of long-lived Mycobacterium tuberculosis-specific Th1-cell like responses.

Ottenhoff TH, Doherty TM, van Dissel JT, Bang P, Lingnau K, Kromann I, Andersen P. Ottenhoff TH, et al. Hum Vaccin. 2010 Dec;6(12):1007-15. doi: 10.4161/hv.6.12.13143. Epub 2010 Dec 1. Hum Vaccin. 2010. PMID: 21178394 Review.

4

Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection.

van Dissel JT, Soonawala D, Joosten SA, Prins C, Arend SM, Bang P, Tingskov PN, Lingnau K, Nouta J, Hoff ST, Rosenkrands I, Kromann I, Ottenhoff TH, Doherty TM, Andersen P. van Dissel JT, et al. Among authors: ottenhoff th. Vaccine. 2011 Mar 3;29(11):2100-9. doi: 10.1016/j.vaccine.2010.12.135. Epub 2011 Jan 20. Vaccine. 2011. PMID: 21256189 Clinical Trial.

5

Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay.

Joosten SA, Goeman JJ, Sutherland JS, Opmeer L, de Boer KG, Jacobsen M, Kaufmann SH, Finos L, Magis-Escurra C, Ota MO, Ottenhoff TH, Haks MC. Joosten SA, et al. Among authors: ottenhoff th. Genes Immun. 2012 Jan;13(1):71-82. doi: 10.1038/gene.2011.64. Epub 2011 Sep 29. Genes Immun. 2012. PMID: 21956656

6

Identification of probable early-onset biomarkers for tuberculosis disease progression.

Sutherland JS, Hill PC, Adetifa IM, de Jong BC, Donkor S, Joosten SA, Opmeer L, Haks MC, Ottenhoff TH, Adegbola RA, Ota MO. Sutherland JS, et al. Among authors: ottenhoff th. PLoS One. 2011;6(9):e25230. doi: 10.1371/journal.pone.0025230. Epub 2011 Sep 23. PLoS One. 2011. PMID: 21966464 Free PMC article.

7

Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting.

Chegou NN, Black GF, Loxton AG, Stanley K, Essone PN, Klein MR, Parida SK, Kaufmann SH, Doherty TM, Friggen AH, Franken KL, Ottenhoff TH, Walzl G. Chegou NN, et al. Among authors: ottenhoff th. BMC Infect Dis. 2012 Jan 20;12:10. doi: 10.1186/1471-2334-12-10. BMC Infect Dis. 2012. PMID: 22260319 Free PMC article.

8

Combination of cytokine responses indicative of latent TB and active TB in Malawian adults.

Hur YG, Gorak-Stolinska P, Ben-Smith A, Lalor MK, Chaguluka S, Dacombe R, Doherty TM, Ottenhoff TH, Dockrell HM, Crampin AC. Hur YG, et al. Among authors: ottenhoff th. PLoS One. 2013 Nov 18;8(11):e79742. doi: 10.1371/journal.pone.0079742. eCollection 2013. PLoS One. 2013. PMID: 24260295 Free PMC article.

9

Identification of immunological biomarkers which may differentiate latent tuberculosis from exposure to environmental nontuberculous mycobacteria in children.

Hur YG, Crampin AC, Chisambo C, Kanyika J, Houben R, Ndhlovu R, Mzembe T, Lalor MK, Saul J, Branson K, Stanley C, Ngwira B, French N, Ottenhoff TH, Dockrell HM, Gorak-Stolinska P. Hur YG, et al. Among authors: ottenhoff th. Clin Vaccine Immunol. 2014 Feb;21(2):133-42. doi: 10.1128/CVI.00620-13. Epub 2013 Nov 27. Clin Vaccine Immunol. 2014. PMID: 24285818 Free PMC article.

10

Longitudinal immune responses and gene expression profiles in type 1 leprosy reactions.

Geluk A, van Meijgaarden KE, Wilson L, Bobosha K, van der Ploeg-van Schip JJ, van den Eeden SJ, Quinten E, Dijkman K, Franken KL, Haisma EM, Haks MC, van Hees CL, Ottenhoff TH. Geluk A, et al. Among authors: ottenhoff th. J Clin Immunol. 2014 Feb;34(2):245-55. doi: 10.1007/s10875-013-9979-x. Epub 2013 Dec 27. J Clin Immunol. 2014. PMID: 24370984

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