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Page 1
Discovery of aminoquinazoline derivatives as human A(2A) adenosine receptor antagonists.
Zhou G, Aslanian R, Gallo G, Khan T, Kuang R, Purakkattle B, De Ruiz M, Stamford A, Ting P, Wu H, Wang H, Xiao D, Yu T, Zhang Y, Mullins D, Hodgson R. Zhou G, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1348-54. doi: 10.1016/j.bmcl.2015.11.048. Epub 2015 Dec 1. Bioorg Med Chem Lett. 2016. PMID: 26781932
The optimization of pyridazinone series of glucan synthase inhibitors.
Kuang R, Wu H, Ting PC, Aslanian RG, Cao J, Kim DW, Lee JF, Schwerdt J, Zhou G, Herr RJ, Zych AJ, Yang J, Lam SQ, Jenkins DM, Sakwa SA, Wainhaus S, Black TA, Cacciapuoti A, McNicholas PM, Xu Y, Walker SS. Kuang R, et al. Among authors: aslanian rg. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5268-71. doi: 10.1016/j.bmcl.2012.06.091. Epub 2012 Jul 4. Bioorg Med Chem Lett. 2012. PMID: 22818082
Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors.
Ting PC, Lee JF, Zorn N, Kim HM, Aslanian RG, Lin M, Smith M, Walker SS, Cook J, Van Heek M, Lachowicz J. Ting PC, et al. Bioorg Med Chem Lett. 2013 Feb 15;23(4):985-8. doi: 10.1016/j.bmcl.2012.12.040. Epub 2012 Dec 21. Bioorg Med Chem Lett. 2013. PMID: 23317570
Discovery of oral and inhaled PDE4 inhibitors.
Ting PC, Lee JF, Kuang R, Cao J, Gu D, Huang Y, Liu Z, Aslanian RG, Feng KI, Prelusky D, Lamca J, House A, Phillips JE, Wang P, Wu P, Lundell D, Chapman RW, Celly CS. Ting PC, et al. Among authors: aslanian rg. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5528-32. doi: 10.1016/j.bmcl.2013.08.056. Epub 2013 Aug 21. Bioorg Med Chem Lett. 2013. PMID: 24018187
Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors.
Zhou G, Ting PC, Wishart G, Zorn N, Aslanian RG, Lin M, Smith M, Walker SS, Cook J, Van Heek M, Lachowicz J. Zhou G, et al. Among authors: aslanian rg. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1790-4. doi: 10.1016/j.bmcl.2014.02.028. Epub 2014 Feb 19. Bioorg Med Chem Lett. 2014. PMID: 24618302
Spiro-piperidine azetidinones as potent TRPV1 antagonists.
Xiao D, Palani A, Aslanian R, McKittrick BA, McPhail AT, Correll CC, Phelps PT, Anthes JC, Rindgen D. Xiao D, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2009 Feb 1;19(3):783-7. doi: 10.1016/j.bmcl.2008.12.024. Epub 2008 Dec 10. Bioorg Med Chem Lett. 2009. PMID: 19114307
SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors.
Zhou G, Ting PC, Aslanian R, Cao J, Kim DW, Kuang R, Lee JF, Schwerdt J, Wu H, Herr RJ, Zych AJ, Yang J, Lam S, Wainhaus S, Black TA, McNicholas PM, Xu Y, Walker SS. Zhou G, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2011 May 15;21(10):2890-3. doi: 10.1016/j.bmcl.2011.03.083. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21489787
Discovery of oxazole-based PDE4 inhibitors with picomolar potency.
Kuang R, Shue HJ, Xiao L, Blythin DJ, Shih NY, Chen X, Gu D, Schwerdt J, Lin L, Ting PC, Cao J, Aslanian R, Piwinski JJ, Prelusky D, Wu P, Zhang J, Zhang X, Celly CS, Billah M, Wang P. Kuang R, et al. Among authors: aslanian r. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2594-7. doi: 10.1016/j.bmcl.2012.01.115. Epub 2012 Feb 14. Bioorg Med Chem Lett. 2012. PMID: 22401864
111 results