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Page 1
Discovery of aminoquinazoline derivatives as human A(2A) adenosine receptor antagonists.
Zhou G, Aslanian R, Gallo G, Khan T, Kuang R, Purakkattle B, De Ruiz M, Stamford A, Ting P, Wu H, Wang H, Xiao D, Yu T, Zhang Y, Mullins D, Hodgson R. Zhou G, et al. Among authors: kuang r. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1348-54. doi: 10.1016/j.bmcl.2015.11.048. Epub 2015 Dec 1. Bioorg Med Chem Lett. 2016. PMID: 26781932
SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors.
Zhou G, Ting PC, Aslanian R, Cao J, Kim DW, Kuang R, Lee JF, Schwerdt J, Wu H, Herr RJ, Zych AJ, Yang J, Lam S, Wainhaus S, Black TA, McNicholas PM, Xu Y, Walker SS. Zhou G, et al. Among authors: kuang r. Bioorg Med Chem Lett. 2011 May 15;21(10):2890-3. doi: 10.1016/j.bmcl.2011.03.083. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21489787
Discovery of oxazole-based PDE4 inhibitors with picomolar potency.
Kuang R, Shue HJ, Xiao L, Blythin DJ, Shih NY, Chen X, Gu D, Schwerdt J, Lin L, Ting PC, Cao J, Aslanian R, Piwinski JJ, Prelusky D, Wu P, Zhang J, Zhang X, Celly CS, Billah M, Wang P. Kuang R, et al. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2594-7. doi: 10.1016/j.bmcl.2012.01.115. Epub 2012 Feb 14. Bioorg Med Chem Lett. 2012. PMID: 22401864
The optimization of pyridazinone series of glucan synthase inhibitors.
Kuang R, Wu H, Ting PC, Aslanian RG, Cao J, Kim DW, Lee JF, Schwerdt J, Zhou G, Herr RJ, Zych AJ, Yang J, Lam SQ, Jenkins DM, Sakwa SA, Wainhaus S, Black TA, Cacciapuoti A, McNicholas PM, Xu Y, Walker SS. Kuang R, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5268-71. doi: 10.1016/j.bmcl.2012.06.091. Epub 2012 Jul 4. Bioorg Med Chem Lett. 2012. PMID: 22818082
Discovery of oral and inhaled PDE4 inhibitors.
Ting PC, Lee JF, Kuang R, Cao J, Gu D, Huang Y, Liu Z, Aslanian RG, Feng KI, Prelusky D, Lamca J, House A, Phillips JE, Wang P, Wu P, Lundell D, Chapman RW, Celly CS. Ting PC, et al. Among authors: kuang r. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5528-32. doi: 10.1016/j.bmcl.2013.08.056. Epub 2013 Aug 21. Bioorg Med Chem Lett. 2013. PMID: 24018187
Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors.
Kuang R, Shue HJ, Blythin DJ, Shih NY, Gu D, Chen X, Schwerdt J, Lin L, Ting PC, Zhu X, Aslanian R, Piwinski JJ, Xiao L, Prelusky D, Wu P, Zhang J, Zhang X, Celly CS, Minnicozzi M, Billah M, Wang P. Kuang R, et al. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5150-4. doi: 10.1016/j.bmcl.2007.06.092. Epub 2007 Jul 7. Bioorg Med Chem Lett. 2007. PMID: 17683932
Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors.
Walker SS, Xu Y, Triantafyllou I, Waldman MF, Mendrick C, Brown N, Mann P, Chau A, Patel R, Bauman N, Norris C, Antonacci B, Gurnani M, Cacciapuoti A, McNicholas PM, Wainhaus S, Herr RJ, Kuang R, Aslanian RG, Ting PC, Black TA. Walker SS, et al. Among authors: kuang r. Antimicrob Agents Chemother. 2011 Nov;55(11):5099-106. doi: 10.1128/AAC.00432-11. Epub 2011 Aug 15. Antimicrob Agents Chemother. 2011. PMID: 21844320 Free PMC article.
246 results