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Page 1
Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes.
Rotroff DM, Shahin MH, Gurley SB, Zhu H, Motsinger-Reif A, Meisner M, Beitelshees AL, Fiehn O, Johnson JA, Elbadawi-Sidhu M, Frye RF, Gong Y, Weng L, Cooper-DeHoff RM, Kaddurah-Daouk R. Rotroff DM, et al. Among authors: zhu h. CPT Pharmacometrics Syst Pharmacol. 2015 Nov;4(11):669-79. doi: 10.1002/psp4.12017. Epub 2015 Oct 29. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26783503 Free PMC article.
Pharmacometabolomics reveals racial differences in response to atenolol treatment.
Wikoff WR, Frye RF, Zhu H, Gong Y, Boyle S, Churchill E, Cooper-Dehoff RM, Beitelshees AL, Chapman AB, Fiehn O, Johnson JA, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Wikoff WR, et al. Among authors: zhu h. PLoS One. 2013;8(3):e57639. doi: 10.1371/journal.pone.0057639. Epub 2013 Mar 11. PLoS One. 2013. PMID: 23536766 Free PMC article.
Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose?
Cooper-Dehoff RM, Hou W, Weng L, Baillie RA, Beitelshees AL, Gong Y, Shahin MH, Turner ST, Chapman A, Gums JG, Boyle SH, Zhu H, Wikoff WR, Boerwinkle E, Fiehn O, Frye RF, Kaddurah-Daouk R, Johnson JA. Cooper-Dehoff RM, et al. Among authors: zhu h. Circ Cardiovasc Genet. 2014 Apr;7(2):199-205. doi: 10.1161/CIRCGENETICS.113.000421. Epub 2014 Mar 13. Circ Cardiovasc Genet. 2014. PMID: 24627569 Free PMC article. Clinical Trial.
Pharmacometabolomic signature links simvastatin therapy and insulin resistance.
Elbadawi-Sidhu M, Baillie RA, Zhu H, Chen YI, Goodarzi MO, Rotter JI, Krauss RM, Fiehn O, Kaddurah-Daouk R. Elbadawi-Sidhu M, et al. Among authors: zhu h. Metabolomics. 2017 Jan;13:11. doi: 10.1007/s11306-016-1141-3. Epub 2016 Dec 23. Metabolomics. 2017. PMID: 29732238 Free PMC article.
Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability.
Ellero-Simatos S, Lewis JP, Georgiades A, Yerges-Armstrong LM, Beitelshees AL, Horenstein RB, Dane A, Harms AC, Ramaker R, Vreeken RJ, Perry CG, Zhu H, Sànchez CL, Kuhn C, Ortel TL, Shuldiner AR, Hankemeier T, Kaddurah-Daouk R. Ellero-Simatos S, et al. Among authors: zhu h. CPT Pharmacometrics Syst Pharmacol. 2014 Jul 16;3(7):e125. doi: 10.1038/psp.2014.22. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25029353 Free PMC article.
Pharmacometabolomics of statin response.
Krauss RM, Zhu H, Kaddurah-Daouk R. Krauss RM, et al. Among authors: zhu h. Clin Pharmacol Ther. 2013 Nov;94(5):562-5. doi: 10.1038/clpt.2013.164. Epub 2013 Aug 14. Clin Pharmacol Ther. 2013. PMID: 23945822 Free PMC article. Review.
Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging.
Motsinger-Reif AA, Zhu H, Kling MA, Matson W, Sharma S, Fiehn O, Reif DM, Appleby DH, Doraiswamy PM, Trojanowski JQ, Kaddurah-Daouk R, Arnold SE. Motsinger-Reif AA, et al. Among authors: zhu h. Acta Neuropathol Commun. 2013 Jun 27;1:28. doi: 10.1186/2051-5960-1-28. Acta Neuropathol Commun. 2013. PMID: 24252434 Free PMC article.
Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics.
Yerges-Armstrong LM, Ellero-Simatos S, Georgiades A, Zhu H, Lewis JP, Horenstein RB, Beitelshees AL, Dane A, Reijmers T, Hankemeier T, Fiehn O, Shuldiner AR, Kaddurah-Daouk R. Yerges-Armstrong LM, et al. Among authors: zhu h. Clin Pharmacol Ther. 2013 Oct;94(4):525-32. doi: 10.1038/clpt.2013.119. Epub 2013 Jun 11. Clin Pharmacol Ther. 2013. PMID: 23839601 Free PMC article. Clinical Trial.
Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway.
Zhu H, Bogdanov MB, Boyle SH, Matson W, Sharma S, Matson S, Churchill E, Fiehn O, Rush JA, Krishnan RR, Pickering E, Delnomdedieu M, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Zhu H, et al. PLoS One. 2013 Jul 17;8(7):e68283. doi: 10.1371/journal.pone.0068283. Print 2013. PLoS One. 2013. PMID: 23874572 Free PMC article. Clinical Trial.
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