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Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Ma Y, Follis JL, Smith CE, Tanaka T, Manichaikul AW, Chu AY, Samieri C, Zhou X, Guan W, Wang L, Biggs ML, Chen YD, Hernandez DG, Borecki I, Chasman DI, Rich SS, Ferrucci L, Irvin MR, Aslibekyan S, Zhi D, Tiwari HK, Claas SA, Sha J, Kabagambe EK, Lai CQ, Parnell LD, Lee YC, Amouyel P, Lambert JC, Psaty BM, King IB, Mozaffarian D, McKnight B, Bandinelli S, Tsai MY, Ridker PM, Ding J, Mstat KL, Liu Y, Sotoodehnia N, Barberger-Gateau P, Steffen LM, Siscovick DS, Absher D, Arnett DK, Ordovás JM, Lemaitre RN. Ma Y, et al. Among authors: chen yd. Am J Clin Nutr. 2016 Feb;103(2):567-78. doi: 10.3945/ajcn.115.112987. Epub 2016 Jan 20. Am J Clin Nutr. 2016. PMID: 26791180 Free PMC article.
Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Lemaitre RN, Tanaka T, Tang W, Manichaikul A, Foy M, Kabagambe EK, Nettleton JA, King IB, Weng LC, Bhattacharya S, Bandinelli S, Bis JC, Rich SS, Jacobs DR Jr, Cherubini A, McKnight B, Liang S, Gu X, Rice K, Laurie CC, Lumley T, Browning BL, Psaty BM, Chen YD, Friedlander Y, Djousse L, Wu JH, Siscovick DS, Uitterlinden AG, Arnett DK, Ferrucci L, Fornage M, Tsai MY, Mozaffarian D, Steffen LM. Lemaitre RN, et al. Among authors: chen yd. PLoS Genet. 2011 Jul;7(7):e1002193. doi: 10.1371/journal.pgen.1002193. Epub 2011 Jul 28. PLoS Genet. 2011. PMID: 21829377 Free PMC article.
Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site.
Richardson K, Nettleton JA, Rotllan N, Tanaka T, Smith CE, Lai CQ, Parnell LD, Lee YC, Lahti J, Lemaitre RN, Manichaikul A, Keller M, Mikkilä V, Ngwa J, van Rooij FJ, Ballentyne CM, Borecki IB, Cupples LA, Garcia M, Hofman A, Ferrucci L, Mozaffarian D, Perälä MM, Raitakari O, Tracy RP, Arnett DK, Bandinelli S, Boerwinkle E, Eriksson JG, Franco OH, Kähönen M, Nalls M, Siscovick DS, Houston DK, Psaty BM, Viikari J, Witteman JC, Goodarzi MO, Lehtimäki T, Liu Y, Zillikens MC, Chen YD, Uitterlinden AG, Rotter JI, Fernandez-Hernando C, Ordovas JM. Richardson K, et al. Among authors: chen yd. Am J Hum Genet. 2013 Jan 10;92(1):5-14. doi: 10.1016/j.ajhg.2012.10.020. Epub 2012 Dec 13. Am J Hum Genet. 2013. PMID: 23246289 Free PMC article.
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
Wu JH, Lemaitre RN, Manichaikul A, Guan W, Tanaka T, Foy M, Kabagambe EK, Djousse L, Siscovick D, Fretts AM, Johnson C, King IB, Psaty BM, McKnight B, Rich SS, Chen YD, Nettleton JA, Tang W, Bandinelli S, Jacobs DR Jr, Browning BL, Laurie CC, Gu X, Tsai MY, Steffen LM, Ferrucci L, Fornage M, Mozaffarian D. Wu JH, et al. Among authors: chen yd. Circ Cardiovasc Genet. 2013 Apr;6(2):171-83. doi: 10.1161/CIRCGENETICS.112.964619. Epub 2013 Jan 29. Circ Cardiovasc Genet. 2013. PMID: 23362303 Free PMC article.
Genetic loci associated with circulating levels of very long-chain saturated fatty acids.
Lemaitre RN, King IB, Kabagambe EK, Wu JH, McKnight B, Manichaikul A, Guan W, Sun Q, Chasman DI, Foy M, Wang L, Zhu J, Siscovick DS, Tsai MY, Arnett DK, Psaty BM, Djousse L, Chen YD, Tang W, Weng LC, Wu H, Jensen MK, Chu AY, Jacobs DR Jr, Rich SS, Mozaffarian D, Steffen L, Rimm EB, Hu FB, Ridker PM, Fornage M, Friedlander Y. Lemaitre RN, et al. Among authors: chen yd. J Lipid Res. 2015 Jan;56(1):176-84. doi: 10.1194/jlr.M052456. Epub 2014 Nov 6. J Lipid Res. 2015. PMID: 25378659 Free PMC article.
Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate.
Aslibekyan S, Goodarzi MO, Frazier-Wood AC, Yan X, Irvin MR, Kim E, Tiwari HK, Guo X, Straka RJ, Taylor KD, Tsai MY, Hopkins PN, Korenman SG, Borecki IB, Chen YD, Ordovas JM, Rotter JI, Arnett DK. Aslibekyan S, et al. Among authors: chen yd. PLoS One. 2012;7(10):e48663. doi: 10.1371/journal.pone.0048663. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23119086 Free PMC article.
Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in Chinese and European-ancestry populations.
Hu Y, Li H, Lu L, Manichaikul A, Zhu J, Chen YD, Sun L, Liang S, Siscovick DS, Steffen LM, Tsai MY, Rich SS, Lemaitre RN, Lin X. Hu Y, et al. Among authors: chen yd. Hum Mol Genet. 2016 Mar 15;25(6):1215-24. doi: 10.1093/hmg/ddw002. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744325 Free PMC article.
Quantitative trait loci on chromosome 8q24 for pancreatic beta-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study.
An P, Freedman BI, Rich SS, Mandel SA, Arnett DK, Myers RH, Chen YD, Hunt SC, Rao DC. An P, et al. Among authors: chen yd. Diabetes. 2006 Feb;55(2):551-8. doi: 10.2337/diabetes.55.02.06.db05-0714. Diabetes. 2006. PMID: 16443794
Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.
Irvin MR, Shrestha S, Chen YD, Wiener HW, Haritunians T, Vaughan LK, Tiwari HK, Taylor KD, Scherzer R, Saag MS, Grunfeld C, Rotter JI, Arnett DK. Irvin MR, et al. Among authors: chen yd. Pharmacogenet Genomics. 2011 Dec;21(12):798-807. doi: 10.1097/FPC.0b013e32834b68f9. Pharmacogenet Genomics. 2011. PMID: 21897333 Free PMC article.
Biological, clinical and population relevance of 95 loci for blood lipids.
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF, Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Man… See abstract for full author list ➔ Teslovich TM, et al. Among authors: chen yd. Nature. 2010 Aug 5;466(7307):707-13. doi: 10.1038/nature09270. Nature. 2010. PMID: 20686565 Free PMC article.
1,273 results