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TAK-228 (formerly MLN0128), an investigational oral dual TORC1/2 inhibitor: A phase I dose escalation study in patients with relapsed or refractory multiple myeloma, non-Hodgkin lymphoma, or Waldenström's macroglobulinemia.
Ghobrial IM, Siegel DS, Vij R, Berdeja JG, Richardson PG, Neuwirth R, Patel CG, Zohren F, Wolf JL. Ghobrial IM, et al. Among authors: zohren f. Am J Hematol. 2016 Jun;91(4):400-5. doi: 10.1002/ajh.24300. Am J Hematol. 2016. PMID: 26800393 Free article. Clinical Trial.
TAK-228 (formerly MLN0128), an investigational dual TORC1/2 inhibitor plus paclitaxel, with/without trastuzumab, in patients with advanced solid malignancies.
Burris HA 3rd, Kurkjian CD, Hart L, Pant S, Murphy PB, Jones SF, Neuwirth R, Patel CG, Zohren F, Infante JR. Burris HA 3rd, et al. Among authors: zohren f. Cancer Chemother Pharmacol. 2017 Aug;80(2):261-273. doi: 10.1007/s00280-017-3343-4. Epub 2017 Jun 10. Cancer Chemother Pharmacol. 2017. PMID: 28601972 Clinical Trial.
A First-in-Human, Phase I, Dose-Escalation Study of TAK-117, a Selective PI3Kα Isoform Inhibitor, in Patients with Advanced Solid Malignancies.
Juric D, de Bono JS, LoRusso PM, Nemunaitis J, Heath EI, Kwak EL, Macarulla Mercadé T, Geuna E, Jose de Miguel-Luken M, Patel C, Kuida K, Sankoh S, Westin EH, Zohren F, Shou Y, Tabernero J. Juric D, et al. Among authors: zohren f. Clin Cancer Res. 2017 Sep 1;23(17):5015-5023. doi: 10.1158/1078-0432.CCR-16-2888. Epub 2017 May 10. Clin Cancer Res. 2017. PMID: 28490463 Free PMC article. Clinical Trial.
Bendamustine in patients with relapsed or refractory multiple myeloma.
Michael M, Bruns I, Bölke E, Zohren F, Czibere A, Safaian NN, Neumann F, Haas R, Kobbe G, Fenk R. Michael M, et al. Among authors: zohren f. Eur J Med Res. 2010 Jan 29;15(1):13-9. doi: 10.1186/2047-783x-15-1-13. Eur J Med Res. 2010. PMID: 20159666 Free PMC article.
Sustained G-CSF plasma levels following administration of pegfilgrastim fasten neutrophil reconstitution after high-dose chemotherapy and autologous blood stem cell transplantation in patients with multiple myeloma.
Fenk R, Hieronimus N, Steidl U, Bruns I, Graef T, Zohren F, Ruf L, Haas R, Kobbe G. Fenk R, et al. Among authors: zohren f. Exp Hematol. 2006 Oct;34(10):1296-302. doi: 10.1016/j.exphem.2006.06.002. Exp Hematol. 2006. PMID: 16982322 Free article.
Reliable engraftment, low toxicity, and durable remissions following allogeneic blood stem cell transplantation with minimal conditioning.
Kobbe G, Schneider P, Aivado M, Zohren F, Schubert D, Fenk R, Neumann F, Kronenwett R, Pape H, Rong A, Royer-Pokora B, Hildebrandt B, Germing U, Gattermann N, Heyll A, Haas R. Kobbe G, et al. Among authors: zohren f. Exp Hematol. 2002 Nov;30(11):1346-53. doi: 10.1016/s0301-472x(02)00923-2. Exp Hematol. 2002. PMID: 12423689 Free article.
The level of minimal residual disease in the bone marrow of patients with multiple myeloma before high-dose therapy and autologous blood stem cell transplantation is an independent predictive parameter.
Korthals M, Sehnke N, Kronenwett R, Bruns I, Mau J, Zohren F, Haas R, Kobbe G, Fenk R. Korthals M, et al. Among authors: zohren f. Biol Blood Marrow Transplant. 2012 Mar;18(3):423-431.e3. doi: 10.1016/j.bbmt.2011.07.002. Epub 2011 Jul 13. Biol Blood Marrow Transplant. 2012. PMID: 21745451 Free article.
Upfront allogeneic blood stem cell transplantation for patients with high-risk myelodysplastic syndrome or secondary acute myeloid leukemia using a FLAMSA-based high-dose sequential conditioning regimen.
Saure C, Schroeder T, Zohren F, Groten A, Bruns I, Czibere A, Galonska L, Kondakci M, Weigelt C, Fenk R, Germing U, Haas R, Kobbe G. Saure C, et al. Among authors: zohren f. Biol Blood Marrow Transplant. 2012 Mar;18(3):466-72. doi: 10.1016/j.bbmt.2011.09.006. Epub 2011 Sep 29. Biol Blood Marrow Transplant. 2012. PMID: 21963618 Free article. Clinical Trial.
43 results