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Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody.
Nguyen VS, Spinelli S, Desmyter A, Le TT, Kellenberger C, Cascales E, Cambillau C, Roussel A. Nguyen VS, et al. Among authors: kellenberger c. Acta Crystallogr F Struct Biol Commun. 2015 Mar;71(Pt 3):266-71. doi: 10.1107/S2053230X15000709. Epub 2015 Feb 19. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25760699 Free PMC article.
Inhibition of type VI secretion by an anti-TssM llama nanobody.
Nguyen VS, Logger L, Spinelli S, Desmyter A, Le TT, Kellenberger C, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C. Nguyen VS, et al. Among authors: kellenberger c. PLoS One. 2015 Mar 26;10(3):e0122187. doi: 10.1371/journal.pone.0122187. eCollection 2015. PLoS One. 2015. PMID: 25811612 Free PMC article.
A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery.
Flaugnatti N, Le TT, Canaan S, Aschtgen MS, Nguyen VS, Blangy S, Kellenberger C, Roussel A, Cambillau C, Cascales E, Journet L. Flaugnatti N, et al. Among authors: kellenberger c. Mol Microbiol. 2016 Mar;99(6):1099-118. doi: 10.1111/mmi.13292. Epub 2016 Feb 10. Mol Microbiol. 2016. PMID: 26714038 Free article.
Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.
Duhoo Y, Roche J, Trinh TTN, Desmyter A, Gaubert A, Kellenberger C, Cambillau C, Roussel A, Leone P. Duhoo Y, et al. Among authors: kellenberger c. Acta Crystallogr F Struct Biol Commun. 2017 May 1;73(Pt 5):286-293. doi: 10.1107/S2053230X17005969. Epub 2017 Apr 26. Acta Crystallogr F Struct Biol Commun. 2017. PMID: 28471361 Free PMC article.
Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nguyen VS, Logger L, Spinelli S, Legrand P, Huyen Pham TT, Nhung Trinh TT, Cherrak Y, Zoued A, Desmyter A, Durand E, Roussel A, Kellenberger C, Cascales E, Cambillau C. Nguyen VS, et al. Among authors: kellenberger c. Nat Microbiol. 2017 Jun 26;2:17103. doi: 10.1038/nmicrobiol.2017.103. Nat Microbiol. 2017. PMID: 28650463
196 results