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USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.
Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M. Laurila PP, et al. Among authors: coomans cp. Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015. Sci Transl Med. 2016. PMID: 26819196
Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity.
Kooijman S, van den Berg R, Ramkisoensing A, Boon MR, Kuipers EN, Loef M, Zonneveld TC, Lucassen EA, Sips HC, Chatzispyrou IA, Houtkooper RH, Meijer JH, Coomans CP, Biermasz NR, Rensen PC. Kooijman S, et al. Among authors: coomans cp. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6748-53. doi: 10.1073/pnas.1504239112. Epub 2015 May 11. Proc Natl Acad Sci U S A. 2015. PMID: 25964318 Free PMC article.
The brain modulates insulin sensitivity in multiple tissues.
Parlevliet ET, Coomans CP, Rensen PC, Romijn JA. Parlevliet ET, et al. Among authors: coomans cp. Front Horm Res. 2014;42:50-8. doi: 10.1159/000358314. Epub 2014 Apr 7. Front Horm Res. 2014. PMID: 24732924 Review.
A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening.
van den Berg R, Kooijman S, Noordam R, Ramkisoensing A, Abreu-Vieira G, Tambyrajah LL, Dijk W, Ruppert P, Mol IM, Kramar B, Caputo R, Puig LS, de Ruiter EM, Kroon J, Hoekstra M, van der Sluis RJ, Meijer OC, Willems van Dijk K, van Kerkhof LWM, Christodoulides C, Karpe F, Gerhart-Hines Z, Kersten S, Meijer JH, Coomans CP, van Heemst D, Biermasz NR, Rensen PCN. van den Berg R, et al. Among authors: coomans cp. Cell Rep. 2018 Mar 27;22(13):3521-3533. doi: 10.1016/j.celrep.2018.03.004. Cell Rep. 2018. PMID: 29590620 Free article.
Continuous Light Does Not Affect Atherosclerosis in APOE*3-Leiden.CETP Mice.
Schilperoort M, van den Berg R, Coomans CP, Khedoe PPSJ, Ramkisoensing A, Boekestijn S, Wang Y, Berbée JFP, Meijer JH, Biermasz NR, Rensen PCN, Kooijman S. Schilperoort M, et al. Among authors: coomans cp. J Biol Rhythms. 2020 Dec;35(6):598-611. doi: 10.1177/0748730420951320. Epub 2020 Sep 11. J Biol Rhythms. 2020. PMID: 32915671 Free PMC article.
Plasticity of circadian clocks and consequences for metabolism.
Coomans CP, Lucassen EA, Kooijman S, Fifel K, Deboer T, Rensen PC, Michel S, Meijer JH. Coomans CP, et al. Diabetes Obes Metab. 2015 Sep;17 Suppl 1:65-75. doi: 10.1111/dom.12513. Diabetes Obes Metab. 2015. PMID: 26332970 Review.
24 results