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USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.
Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M. Laurila PP, et al. Among authors: makela a. Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015. Sci Transl Med. 2016. PMID: 26819196
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
Kastaniotis AJ, Autio KJ, Kerätär JM, Monteuuis G, Mäkelä AM, Nair RR, Pietikäinen LP, Shvetsova A, Chen Z, Hiltunen JK. Kastaniotis AJ, et al. Among authors: makela am. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jan;1862(1):39-48. doi: 10.1016/j.bbalip.2016.08.011. Epub 2016 Aug 21. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27553474 Review.
Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders.
Hoheisel L, Kambeitz-Ilankovic L, Wenzel J, Haas SS, Antonucci LA, Ruef A, Penzel N, Schultze-Lutter F, Lichtenstein T, Rosen M, Dwyer DB, Salokangas RKR, Lencer R, Brambilla P, Borgwardt S, Wood SJ, Upthegrove R, Bertolino A, Ruhrmann S, Meisenzahl E, Koutsouleris N, Fink GR, Daun S, Kambeitz J; PRONIA Consortium. Hoheisel L, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Mar 8:S2451-9022(24)00065-X. doi: 10.1016/j.bpsc.2024.02.013. Online ahead of print. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024. PMID: 38461964 Free article.
A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol.
Barbera M, Lehtisalo J, Perera D, Aspö M, Cross M, De Jager Loots CA, Falaschetti E, Friel N, Luchsinger JA, Gavelin HM, Peltonen M, Price G, Neely AS, Thunborg C, Tuomilehto J, Mangialasche F, Middleton L, Ngandu T, Solomon A, Kivipelto M; MET-FINGER study team. Barbera M, et al. Alzheimers Res Ther. 2024 Jan 31;16(1):23. doi: 10.1186/s13195-023-01355-x. Alzheimers Res Ther. 2024. PMID: 38297399 Free PMC article.
Liprin-α1 contributes to oncogenic MAPK signaling by counteracting ERK activity.
Pehkonen H, Filippou A, Väänänen J, Lindfors I, Vänttinen M, Ianevski P, Mäkelä A, Munne P, Klefström J, Toppila-Salmi S, Grénman R, Hagström J, Mäkitie AA, Karhemo PR, Monni O. Pehkonen H, et al. Among authors: makela a. Mol Oncol. 2024 Mar;18(3):662-676. doi: 10.1002/1878-0261.13593. Epub 2024 Jan 24. Mol Oncol. 2024. PMID: 38264964 Free PMC article.
Polylactide Degradation Activates Immune Cells by Metabolic Reprogramming.
Maduka CV, Alhaj M, Ural E, Habeeb OM, Kuhnert MM, Smith K, Makela AV, Pope H, Chen S, Hix JM, Mallett CL, Chung SJ, Hakun M, Tundo A, Zinn KR, Hankenson KD, Goodman SB, Narayan R, Contag CH. Maduka CV, et al. Among authors: makela av. Adv Sci (Weinh). 2023 Nov;10(31):e2304632. doi: 10.1002/advs.202304632. Epub 2023 Sep 22. Adv Sci (Weinh). 2023. PMID: 37737614 Free PMC article.
Transdiagnostic subgroups of cognitive impairment in early affective and psychotic illness.
Wenzel J, Badde L, Haas SS, Bonivento C, Van Rheenen TE, Antonucci LA, Ruef A, Penzel N, Rosen M, Lichtenstein T, Lalousis PA, Paolini M, Stainton A, Dannlowski U, Romer G, Brambilla P, Wood SJ, Upthegrove R, Borgwardt S, Meisenzahl E, Salokangas RKR, Pantelis C, Lencer R, Bertolino A, Kambeitz J, Koutsouleris N, Dwyer DB, Kambeitz-Ilankovic L; PRONIA consortium. Wenzel J, et al. Neuropsychopharmacology. 2024 Feb;49(3):573-583. doi: 10.1038/s41386-023-01729-7. Epub 2023 Sep 22. Neuropsychopharmacology. 2024. PMID: 37737273 Free PMC article.
Shape Anisotropy-Governed High-Performance Nanomagnetosol for In Vivo Magnetic Particle Imaging of Lungs.
Nigam S, Mohapatra J, Makela AV, Hayat H, Rodriguez JM, Sun A, Kenyon E, Redman NA, Spence D, Jabin G, Gu B, Ashry M, Sempere LF, Mitra A, Li J, Chen J, Wei GW, Bolin S, Etchebarne B, Liu JP, Contag CH, Wang P. Nigam S, et al. Among authors: makela av. Small. 2024 Feb;20(5):e2305300. doi: 10.1002/smll.202305300. Epub 2023 Sep 21. Small. 2024. PMID: 37735143
240 results