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Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
Khersonsky O, Lipsh R, Avizemer Z, Ashani Y, Goldsmith M, Leader H, Dym O, Rogotner S, Trudeau DL, Prilusky J, Amengual-Rigo P, Guallar V, Tawfik DS, Fleishman SJ. Khersonsky O, et al. Mol Cell. 2018 Oct 4;72(1):178-186.e5. doi: 10.1016/j.molcel.2018.08.033. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270109 Free PMC article.
Design and in vitro realization of carbon-conserving photorespiration.
Trudeau DL, Edlich-Muth C, Zarzycki J, Scheffen M, Goldsmith M, Khersonsky O, Avizemer Z, Fleishman SJ, Cotton CAR, Erb TJ, Tawfik DS, Bar-Even A. Trudeau DL, et al. Among authors: khersonsky o. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11455-E11464. doi: 10.1073/pnas.1812605115. Epub 2018 Nov 20. Proc Natl Acad Sci U S A. 2018. PMID: 30459276 Free PMC article.
A Rationally and Computationally Designed Fluorescent Biosensor for d-Serine.
Vongsouthi V, Whitfield JH, Unichenko P, Mitchell JA, Breithausen B, Khersonsky O, Kremers L, Janovjak H, Monai H, Hirase H, Fleishman SJ, Henneberger C, Jackson CJ. Vongsouthi V, et al. Among authors: khersonsky o. ACS Sens. 2021 Nov 26;6(11):4193-4205. doi: 10.1021/acssensors.1c01803. Epub 2021 Nov 16. ACS Sens. 2021. PMID: 34783546
Computationally designed hyperactive Cas9 enzymes.
Vos PD, Rossetti G, Mantegna JL, Siira SJ, Gandadireja AP, Bruce M, Raven SA, Khersonsky O, Fleishman SJ, Filipovska A, Rackham O. Vos PD, et al. Among authors: khersonsky o. Nat Commun. 2022 May 31;13(1):3023. doi: 10.1038/s41467-022-30598-9. Nat Commun. 2022. PMID: 35641498 Free PMC article.
30 results