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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, Jones A, Beck S, Wagner W, Laird PW, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: beck s. Genome Res. 2010 Apr;20(4):440-6. doi: 10.1101/gr.103606.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219944 Free PMC article.
Taking the measure of the methylome.
Beck S. Beck S. Nat Biotechnol. 2010 Oct;28(10):1026-8. doi: 10.1038/nbt1010-1026. Nat Biotechnol. 2010. PMID: 20944589
Methylome analysis using MeDIP-seq with low DNA concentrations.
Taiwo O, Wilson GA, Morris T, Seisenberger S, Reik W, Pearce D, Beck S, Butcher LM. Taiwo O, et al. Among authors: beck s. Nat Protoc. 2012 Mar 8;7(4):617-36. doi: 10.1038/nprot.2012.012. Nat Protoc. 2012. PMID: 22402632
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S. Lechner M, et al. Among authors: beck s. Genome Med. 2013 Feb 5;5(2):15. doi: 10.1186/gm419. eCollection 2013. Genome Med. 2013. PMID: 23419152 Free PMC article.
1,967 results