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Airway acidification initiates host defense abnormalities in cystic fibrosis mice.
Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ. Shah VS, et al. Among authors: karp ph. Science. 2016 Jan 29;351(6272):503-7. doi: 10.1126/science.aad5589. Science. 2016. PMID: 26823428 Free PMC article.
CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo.
Ostedgaard LS, Zabner J, Vermeer DW, Rokhlina T, Karp PH, Stecenko AA, Randak C, Welsh MJ. Ostedgaard LS, et al. Among authors: karp ph. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3093-8. doi: 10.1073/pnas.261714599. Epub 2002 Feb 19. Proc Natl Acad Sci U S A. 2002. PMID: 11854474 Free PMC article.
Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.
Farmen SL, Karp PH, Ng P, Palmer DJ, Koehler DR, Hu J, Beaudet AL, Zabner J, Welsh MJ. Farmen SL, et al. Among authors: karp ph. Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1123-30. doi: 10.1152/ajplung.00049.2005. Epub 2005 Aug 5. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 16085675 Free article.
Differentiation of human airway epithelia is dependent on erbB2.
Vermeer PD, Panko L, Karp P, Lee JH, Zabner J. Vermeer PD, et al. Am J Physiol Lung Cell Mol Physiol. 2006 Aug;291(2):L175-80. doi: 10.1152/ajplung.00547.2005. Epub 2006 Feb 17. Am J Physiol Lung Cell Mol Physiol. 2006. PMID: 16489114 Free article.
55 results