Fleishman SJ - Search Results

1

Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane.

Elazar A, Weinstein J, Biran I, Fridman Y, Bibi E, Fleishman SJ. Elazar A, et al. Among authors: fleishman sj. Elife. 2016 Jan 29;5:e12125. doi: 10.7554/eLife.12125. Elife. 2016. PMID: 26824389 Free PMC article.

2

Computational protein design suggests that human PCNA-partner interactions are not optimized for affinity.

Fridman Y, Gur E, Fleishman SJ, Aharoni A. Fridman Y, et al. Among authors: fleishman sj. Proteins. 2013 Feb;81(2):341-8. doi: 10.1002/prot.24190. Epub 2012 Oct 26. Proteins. 2013. PMID: 23011891

3

Combined Crystal Structure of a Type I Cohesin: MUTATION AND AFFINITY BINDING STUDIES REVEAL STRUCTURAL DETERMINANTS OF COHESIN-DOCKERIN SPECIFICITIES.

Cameron K, Weinstein JY, Zhivin O, Bule P, Fleishman SJ, Alves VD, Gilbert HJ, Ferreira LM, Fontes CM, Bayer EA, Najmudin S. Cameron K, et al. Among authors: fleishman sj. J Biol Chem. 2015 Jun 26;290(26):16215-25. doi: 10.1074/jbc.M115.653303. Epub 2015 May 1. J Biol Chem. 2015. PMID: 25934389 Free PMC article.

4

Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topology.

Elazar A, Weinstein JJ, Prilusky J, Fleishman SJ. Elazar A, et al. Among authors: fleishman sj. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10340-5. doi: 10.1073/pnas.1605888113. Epub 2016 Aug 25. Proc Natl Acad Sci U S A. 2016. PMID: 27562165 Free PMC article.

5

A lipophilicity-based energy function for membrane-protein modelling and design.

Weinstein JY, Elazar A, Fleishman SJ. Weinstein JY, et al. Among authors: fleishman sj. PLoS Comput Biol. 2019 Aug 28;15(8):e1007318. doi: 10.1371/journal.pcbi.1007318. eCollection 2019 Aug. PLoS Comput Biol. 2019. PMID: 31461441 Free PMC article.

6

Practically useful protein-design methods combining phylogenetic and atomistic calculations.

Weinstein J, Khersonsky O, Fleishman SJ. Weinstein J, et al. Among authors: fleishman sj. Curr Opin Struct Biol. 2020 Aug;63:58-64. doi: 10.1016/j.sbi.2020.04.003. Epub 2020 Jun 5. Curr Opin Struct Biol. 2020. PMID: 32505941 Free PMC article. Review.

7

PROSS 2: a new server for the design of stable and highly expressed protein variants.

Weinstein JJ, Goldenzweig A, Hoch S, Fleishman SJ. Weinstein JJ, et al. Among authors: fleishman sj. Bioinformatics. 2021 Apr 9;37(1):123-125. doi: 10.1093/bioinformatics/btaa1071. Bioinformatics. 2021. PMID: 33367682 Free PMC article.

8

Stabilization of the SARS-CoV-2 Receptor Binding Domain by Protein Core Redesign and Deep Mutational Scanning.

Leonard AC, Weinstein JJ, Steiner PJ, Erbse AH, Fleishman SJ, Whitehead TA. Leonard AC, et al. Among authors: fleishman sj. bioRxiv [Preprint]. 2021 Nov 24:2021.11.22.469552. doi: 10.1101/2021.11.22.469552. bioRxiv. 2021. PMID: 34845448 Free PMC article. Updated. Preprint.

9

Structure and receptor recognition by the Lassa virus spike complex.

Katz M, Weinstein J, Eilon-Ashkenazy M, Gehring K, Cohen-Dvashi H, Elad N, Fleishman SJ, Diskin R. Katz M, et al. Among authors: fleishman sj. Nature. 2022 Mar;603(7899):174-179. doi: 10.1038/s41586-022-04429-2. Epub 2022 Feb 16. Nature. 2022. PMID: 35173332

10

Stable and Functionally Diverse Versatile Peroxidases Designed Directly from Sequences.

Barber-Zucker S, Mindel V, Garcia-Ruiz E, Weinstein JJ, Alcalde M, Fleishman SJ. Barber-Zucker S, et al. Among authors: fleishman sj. J Am Chem Soc. 2022 Mar 2;144(8):3564-3571. doi: 10.1021/jacs.1c12433. Epub 2022 Feb 18. J Am Chem Soc. 2022. PMID: 35179866 Free PMC article.

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