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Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration.
Zacchigna S, Oh H, Wilsch-Bräuninger M, Missol-Kolka E, Jászai J, Jansen S, Tanimoto N, Tonagel F, Seeliger M, Huttner WB, Corbeil D, Dewerchin M, Vinckier S, Moons L, Carmeliet P. Zacchigna S, et al. Among authors: huttner wb. J Neurosci. 2009 Feb 18;29(7):2297-308. doi: 10.1523/JNEUROSCI.2034-08.2009. J Neurosci. 2009. PMID: 19228982 Free PMC article.
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.
Saito K, Dubreuil V, Arai Y, Wilsch-Bräuninger M, Schwudke D, Saher G, Miyata T, Breier G, Thiele C, Shevchenko A, Nave KA, Huttner WB. Saito K, et al. Among authors: huttner wb. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8350-5. doi: 10.1073/pnas.0903541106. Epub 2009 May 5. Proc Natl Acad Sci U S A. 2009. PMID: 19416849 Free PMC article.
Haematopoietic stem cell differentiation promotes the release of prominin-1/CD133-containing membrane vesicles--a role of the endocytic-exocytic pathway.
Bauer N, Wilsch-Bräuninger M, Karbanová J, Fonseca AV, Strauss D, Freund D, Thiele C, Huttner WB, Bornhäuser M, Corbeil D. Bauer N, et al. Among authors: huttner wb. EMBO Mol Med. 2011 Jul;3(7):398-409. doi: 10.1002/emmm.201100147. Epub 2011 May 18. EMBO Mol Med. 2011. PMID: 21591261 Free PMC article.
N-cadherin specifies first asymmetry in developing neurons.
Gärtner A, Fornasiero EF, Munck S, Vennekens K, Seuntjens E, Huttner WB, Valtorta F, Dotti CG. Gärtner A, et al. Among authors: huttner wb. EMBO J. 2012 Apr 18;31(8):1893-903. doi: 10.1038/emboj.2012.41. Epub 2012 Feb 21. EMBO J. 2012. PMID: 22354041 Free PMC article.
345 results