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Page 1
Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression.
Tatler AL, Habgood A, Porte J, John AE, Stavrou A, Hodge E, Kerama-Likoko C, Violette SM, Weinreb PH, Knox AJ, Laurent G, Parfrey H, Wolters PJ, Wallace W, Alberti S, Nordheim A, Jenkins G. Tatler AL, et al. Among authors: parfrey h. J Biol Chem. 2016 Apr 29;291(18):9540-53. doi: 10.1074/jbc.M115.692368. Epub 2016 Feb 9. J Biol Chem. 2016. PMID: 26861876 Free PMC article.
Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury.
Taquet M, Skorniewska Z, Zetterberg H, Geddes JR, Mummery CJ, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Raman B, Leavy OC, Richardson M, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, Houchen-Wolloff L, Mansoori P, Greening NJ, Harrison EM, Docherty AB, Lone NI, Quint J, Greenhalf W, Wain LV, Brightling CE, Evans RE, Harrison PJ, Koychev I; PHOSP-COVID Study Collaborative Group. Taquet M, et al. Brain Commun. 2023 Dec 27;6(1):fcad357. doi: 10.1093/braincomms/fcad357. eCollection 2024. Brain Commun. 2023. PMID: 38229877 Free PMC article.
Genome-wide SNP-sex interaction analysis of susceptibility to idiopathic pulmonary fibrosis.
Leavy OC, Goemans AF, Stockwell AD, Allen RJ, Guillen-Guio B, Hernandez-Beeftink T, Adegunsoye A, Booth HL; CleanUP-IPF Investigators of the Pulmonary Trials Cooperative; Cullinan P, Fahy WA, Fingerlin TE, Virk HS, Hall IP, Hart SP, Hill MR, Hirani N, Hubbard RB, Kaminski N, Ma SF, McAnulty RJ, Sheng XR, Millar AB, Molina-Molina M, Navaratnam V, Neighbors M, Parfrey H, Saini G, Sayers I, Strek ME, Tobin MD, Whyte MK, Zhang Y, Maher TM, Molyneaux PL, Oldham JM, Yaspan BL, Flores C, Martinez F, Reynolds CJ, Schwartz DA, Noth I, Jenkins RG, Wain LV. Leavy OC, et al. Among authors: parfrey h. medRxiv [Preprint]. 2024 Jan 15:2024.01.12.24301204. doi: 10.1101/2024.01.12.24301204. medRxiv. 2024. PMID: 38293162 Free PMC article. Preprint.
Long COVID research: an update from the PHOSP-COVID Scientific Summit.
Brightling CE, Evans RA, Singapuri A, Smith N, Wain LV; PHOSP-COVID Collaborative Group. Brightling CE, et al. Lancet Respir Med. 2023 Nov;11(11):e93-e94. doi: 10.1016/S2213-2600(23)00341-7. Epub 2023 Oct 16. Lancet Respir Med. 2023. PMID: 37858329 No abstract available.
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls.
Zheng B, Vivaldi G, Daines L, Leavy OC, Richardson M, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC, Houchen-Wolloff L, Greening NJ, Pfeffer PE, Hurst JR, Brown JS, Shankar-Hari M, Echevarria C, De Soyza A, Harrison EM, Docherty AB, Lone N, Quint JK, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Raman B, Heaney LG, Wain LV, Evans RA, Brightling CE, Martineau A, Sheikh A; PHOSP-COVID Study Collaborative Group. Zheng B, et al. Lancet Reg Health Eur. 2023 Apr 28;29:100635. doi: 10.1016/j.lanepe.2023.100635. eCollection 2023 Jun. Lancet Reg Health Eur. 2023. PMID: 37261214 Free PMC article.
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination.
Liew F, Talwar S, Cross A, Willett BJ, Scott S, Logan N, Siggins MK, Swieboda D, Sidhu JK, Efstathiou C, Moore SC, Davis C, Mohamed N, Nunag J, King C, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard L, Wootton DG, Dunachie S, Quint JK, Evans RA, Wain LV, Fontanella S, de Silva TI, Ho A, Harrison E, Baillie JK, Semple MG, Brightling C, Thwaites RS, Turtle L, Openshaw PJM; ISARIC4C Investigators; PHOSP-COVID collaborative group. Liew F, et al. EBioMedicine. 2023 Jan;87:104402. doi: 10.1016/j.ebiom.2022.104402. Epub 2022 Dec 19. EBioMedicine. 2023. PMID: 36543718 Free PMC article.
Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial.
Maher TM, Tudor VA, Saunders P, Gibbons MA, Fletcher SV, Denton CP, Hoyles RK, Parfrey H, Renzoni EA, Kokosi M, Wells AU, Ashby D, Szigeti M, Molyneaux PL; RECITAL Investigators. Maher TM, et al. Among authors: parfrey h. Lancet Respir Med. 2023 Jan;11(1):45-54. doi: 10.1016/S2213-2600(22)00359-9. Epub 2022 Nov 11. Lancet Respir Med. 2023. PMID: 36375479 Free article. Clinical Trial.
Accelarated immune ageing is associated with COVID-19 disease severity.
Lord JM, Veenith T, Sullivan J, Sharma-Oates A, Richter AG, Greening NJ, McAuley HJC, Evans RA, Moss P, Moore SC, Turtle L, Gautam N, Gilani A, Bajaj M, Wain LV, Brightling C, Raman B, Marks M, Singapuri A, Elneima O, Openshaw PJM, Duggal NA; PHOSP-COVID Study collaborative group; ISARIC4C investigators. Lord JM, et al. Immun Ageing. 2024 Jan 11;21(1):6. doi: 10.1186/s12979-023-00406-z. Immun Ageing. 2024. PMID: 38212801 Free PMC article.
In search of the fibrotic epithelial cell: opportunities for a collaborative network.
Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P; ECIPF workshop. Jenkins G, et al. Among authors: parfrey h. Thorax. 2012 Feb;67(2):179-82. doi: 10.1136/thoraxjnl-2011-200195. Epub 2011 Jun 15. Thorax. 2012. PMID: 21680569
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis.
Tatler AL, Goodwin AT, Gbolahan O, Saini G, Porte J, John AE, Clifford RL, Violette SM, Weinreb PH, Parfrey H, Wolters PJ, Gauldie J, Kolb M, Jenkins G. Tatler AL, et al. Among authors: parfrey h. PLoS One. 2016 Aug 5;11(8):e0158047. doi: 10.1371/journal.pone.0158047. eCollection 2016. PLoS One. 2016. PMID: 27494713 Free PMC article.
90 results