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Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.
Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M. Schieck M, et al. Among authors: granell r. J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20. J Allergy Clin Immunol. 2016. PMID: 26906082
Early childhood wheezing phenotypes and determinants in a South African birth cohort: longitudinal analysis of the Drakenstein Child Health Study.
McCready C, Haider S, Little F, Nicol MP, Workman L, Gray DM, Granell R, Stein DJ, Custovic A, Zar HJ. McCready C, et al. Among authors: granell r. Lancet Child Adolesc Health. 2023 Feb;7(2):127-135. doi: 10.1016/S2352-4642(22)00304-2. Epub 2022 Nov 23. Lancet Child Adolesc Health. 2023. PMID: 36435180 Free PMC article.
The search for new asthma phenotypes.
Henderson J, Granell R, Sterne J. Henderson J, et al. Among authors: granell r. Arch Dis Child. 2009 May;94(5):333-6. doi: 10.1136/adc.2008.143636. Epub 2009 Jan 15. Arch Dis Child. 2009. PMID: 19147620 Review. No abstract available.
A large-scale, consortium-based genomewide association study of asthma.
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM; GABRIEL Consortium. Moffatt MF, et al. N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312. N Engl J Med. 2010. PMID: 20860503 Free PMC article.
Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA.
Savenije OE, Granell R, Caudri D, Koppelman GH, Smit HA, Wijga A, de Jongste JC, Brunekreef B, Sterne JA, Postma DS, Henderson J, Kerkhof M. Savenije OE, et al. Among authors: granell r. J Allergy Clin Immunol. 2011 Jun;127(6):1505-12.e14. doi: 10.1016/j.jaci.2011.02.002. Epub 2011 Mar 16. J Allergy Clin Immunol. 2011. PMID: 21411131
Meta-analysis of mould and dampness exposure on asthma and allergy in eight European birth cohorts: an ENRIECO initiative.
Tischer CG, Hohmann C, Thiering E, Herbarth O, Müller A, Henderson J, Granell R, Fantini MP, Luciano L, Bergström A, Kull I, Link E, von Berg A, Kuehni CE, Strippoli MP, Gehring U, Wijga A, Eller E, Bindslev-Jensen C, Keil T, Heinrich J; ENRIECO consortium. Tischer CG, et al. Among authors: granell r. Allergy. 2011 Dec;66(12):1570-9. doi: 10.1111/j.1398-9995.2011.02712.x. Epub 2011 Sep 19. Allergy. 2011. PMID: 21923669
129 results