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Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.
Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M. Schieck M, et al. Among authors: lipinski s. J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20. J Allergy Clin Immunol. 2016. PMID: 26906082
A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.
Fischer A, Schmid B, Ellinghaus D, Nothnagel M, Gaede KI, Schürmann M, Lipinski S, Rosenstiel P, Zissel G, Höhne K, Petrek M, Kolek V, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Gieger C, Wichmann HE, Nebel A, Franke A, Müller-Quernheim J, Hofmann S, Schreiber S. Fischer A, et al. Among authors: lipinski s. Am J Respir Crit Care Med. 2012 Nov 1;186(9):877-85. doi: 10.1164/rccm.201204-0708OC. Epub 2012 Jul 26. Am J Respir Crit Care Med. 2012. PMID: 22837380
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.
Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Stade B, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Häsler R, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V, Vogel U, Kupcinskas L, Kayser M, Krawczak M, Nikolaus S, Weersma RK, Ponsioen CY, Sans M, Wijmenga C, Strachan DP, McArdle WL, Vermeire S, Rutgeerts P, Sanderson JD, Mathew CG, Vatn MH, Wang J, Nöthen MM, Duerr RH, Büning C, Brand S, Glas J, Winkelmann J, Illig T, Latiano A, Annese V, Halfvarson J, D'Amato M, Daly MJ, Nothnagel M, Karlsen TH, Subramani S, Rosenstiel P, Schreiber S, Parkes M, Franke A. Ellinghaus D, et al. Among authors: lipinski s. Gastroenterology. 2013 Aug;145(2):339-47. doi: 10.1053/j.gastro.2013.04.040. Epub 2013 Apr 25. Gastroenterology. 2013. PMID: 23624108 Free PMC article.
Autophagy receptor CALCOCO2/NDP52 takes center stage in Crohn disease.
Till A, Lipinski S, Ellinghaus D, Mayr G, Subramani S, Rosenstiel P, Franke A. Till A, et al. Among authors: lipinski s. Autophagy. 2013 Aug;9(8):1256-7. doi: 10.4161/auto.25483. Epub 2013 Jun 28. Autophagy. 2013. PMID: 23820297 Free PMC article.
A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.
Schaarschmidt H, Ellinghaus D, Rodríguez E, Kretschmer A, Baurecht H, Lipinski S, Meyer-Hoffert U, Harder J, Lieb W, Novak N, Fölster-Holst R, Esparza-Gordillo J, Marenholz I, Ruschendorf F, Hubner N, Reischl E, Waldenberger M, Gieger C, Illig T, Kabesch M, Zhang XJ, Xiao FL, Lee YA, Franke A, Weidinger S. Schaarschmidt H, et al. Among authors: lipinski s. J Allergy Clin Immunol. 2015 Sep;136(3):802-6. doi: 10.1016/j.jaci.2015.01.047. Epub 2015 Apr 10. J Allergy Clin Immunol. 2015. PMID: 25865352 No abstract available.
Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2.
Lipinski S, Petersen BS, Barann M, Piecyk A, Tran F, Mayr G, Jentzsch M, Aden K, Stengel ST, Klostermeier UC, Sheth V, Ellinghaus D, Rausch T, Korbel JO, Nothnagel M, Krawczak M, Gilissen C, Veltman JA, Forster M, Forster P, Lee CC, Fritscher-Ravens A, Schreiber S, Franke A, Rosenstiel P. Lipinski S, et al. Cold Spring Harb Mol Case Stud. 2019 Feb 1;5(1):a002428. doi: 10.1101/mcs.a002428. Print 2019 Feb. Cold Spring Harb Mol Case Stud. 2019. PMID: 30709874 Free PMC article.
Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.
Billmann-Born S, Till A, Arlt A, Lipinski S, Sina C, Latiano A, Annese V, Häsler R, Kerick M, Manke T, Seegert D, Hanidu A, Schäfer H, van Heel D, Li J, Schreiber S, Rosenstiel P. Billmann-Born S, et al. Among authors: lipinski s. J Immunol. 2011 Apr 1;186(7):4027-38. doi: 10.4049/jimmunol.1000085. Epub 2011 Feb 18. J Immunol. 2011. PMID: 21335489
85 results