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Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.
Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M. Schieck M, et al. Among authors: pershagen g. J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20. J Allergy Clin Immunol. 2016. PMID: 26906082
Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma.
Melén E, Bruce S, Doekes G, Kabesch M, Laitinen T, Lauener R, Lindgren CM, Riedler J, Scheynius A, van Hage-Hamsten M, Kere J, Pershagen G, Wickman M, Nyberg F; PARSIFAL Genetics Study Group. Melén E, et al. Among authors: pershagen g. Am J Respir Crit Care Med. 2005 May 15;171(10):1089-95. doi: 10.1164/rccm.200410-1317OC. Epub 2005 Feb 11. Am J Respir Crit Care Med. 2005. PMID: 15710598
Breast-feeding reduces the risk for childhood eczema.
Kull I, Böhme M, Wahlgren CF, Nordvall L, Pershagen G, Wickman M. Kull I, et al. Among authors: pershagen g. J Allergy Clin Immunol. 2005 Sep;116(3):657-61. doi: 10.1016/j.jaci.2005.04.028. J Allergy Clin Immunol. 2005. PMID: 16159639
Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children.
Ege MJ, Bieli C, Frei R, van Strien RT, Riedler J, Ublagger E, Schram-Bijkerk D, Brunekreef B, van Hage M, Scheynius A, Pershagen G, Benz MR, Lauener R, von Mutius E, Braun-Fahrländer C; Parsifal Study team. Ege MJ, et al. Among authors: pershagen g. J Allergy Clin Immunol. 2006 Apr;117(4):817-23. doi: 10.1016/j.jaci.2005.12.1307. Epub 2006 Feb 7. J Allergy Clin Immunol. 2006. PMID: 16630939
Not all farming environments protect against the development of asthma and wheeze in children.
Ege MJ, Frei R, Bieli C, Schram-Bijkerk D, Waser M, Benz MR, Weiss G, Nyberg F, van Hage M, Pershagen G, Brunekreef B, Riedler J, Lauener R, Braun-Fahrländer C, von Mutius E; PARSIFAL Study team. Ege MJ, et al. Among authors: pershagen g. J Allergy Clin Immunol. 2007 May;119(5):1140-7. doi: 10.1016/j.jaci.2007.01.037. Epub 2007 Mar 8. J Allergy Clin Immunol. 2007. PMID: 17349684
A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression.
Bieli C, Eder W, Frei R, Braun-Fahrländer C, Klimecki W, Waser M, Riedler J, von Mutius E, Scheynius A, Pershagen G, Doekes G, Lauener R, Martinez FD; PARSIFAL study group. Bieli C, et al. Among authors: pershagen g. J Allergy Clin Immunol. 2007 Dec;120(6):1308-15. doi: 10.1016/j.jaci.2007.07.034. Epub 2007 Oct 24. J Allergy Clin Immunol. 2007. PMID: 17919709
Domestic cat allergen and allergic sensitisation in young children.
Chen CM, Gehring U, Wickman M, Hoek G, Giovannangelo M, Nordling E, Wijga A, de Jongste J, Pershagen G, Almqvist C, Kerkhof M, Bellander T, Wichmann HE, Brunekreef B, Heinrich J. Chen CM, et al. Among authors: pershagen g. Int J Hyg Environ Health. 2008 Jul;211(3-4):337-44. doi: 10.1016/j.ijheh.2007.05.007. Epub 2007 Nov 5. Int J Hyg Environ Health. 2008. PMID: 17980657
428 results