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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP; T2D-GENES Consortium. Horikoshi M, et al. Among authors: hanis cl. Hum Mol Genet. 2016 May 15;25(10):2070-2081. doi: 10.1093/hmg/ddw048. Epub 2016 Feb 23. Hum Mol Genet. 2016. PMID: 26911676 Free PMC article.
An approach for identifying simple sequence repeat DNA polymorphisms near cloned cDNAs and genes. Linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM.
Gambino V, Menzel S, Trabb JB, Xiang KS, Lindner T, Louït A, Chen E, Mereu LE, Furuta H, Iwasaki N, Kawamura M, Omori Y, Rietzsch H, Schulze J, Schröder HE, Concannon P, Hanis CL, Spielman RS, Yamagata K, Cox NJ, Bell GI. Gambino V, et al. Among authors: hanis cl. Diabetes. 1996 Mar;45(3):291-4. doi: 10.2337/diab.45.3.291. Diabetes. 1996. PMID: 8593932
A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.
Hanis CL, Boerwinkle E, Chakraborty R, Ellsworth DL, Concannon P, Stirling B, Morrison VA, Wapelhorst B, Spielman RS, Gogolin-Ewens KJ, Shepard JM, Williams SR, Risch N, Hinds D, Iwasaki N, Ogata M, Omori Y, Petzold C, Rietzch H, Schröder HE, Schulze J, Cox NJ, Menzel S, Boriraj VV, Chen X, Lim LR, Lindner T, Mereu LE, Wang YQ, Xiang K, Yamagata K, Yang Y, Bell GI. Hanis CL, et al. Nat Genet. 1996 Jun;13(2):161-6. doi: 10.1038/ng0696-161. Nat Genet. 1996. PMID: 8640221
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI. Horikawa Y, et al. Among authors: hanis cl. Nat Genet. 2000 Oct;26(2):163-75. doi: 10.1038/79876. Nat Genet. 2000. PMID: 11017071
228 results