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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP; T2D-GENES Consortium. Horikoshi M, et al. Among authors: hara k. Hum Mol Genet. 2016 May 15;25(10):2070-2081. doi: 10.1093/hmg/ddw048. Epub 2016 Feb 23. Hum Mol Genet. 2016. PMID: 26911676 Free PMC article.
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.
Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T. Hara K, et al. Diabetes. 2002 Feb;51(2):536-40. doi: 10.2337/diabetes.51.2.536. Diabetes. 2002. PMID: 11812766
[Current status of analysis of type 2 diabetes genes].
Kadowaki T, Hara K, Mori Y. Kadowaki T, et al. Among authors: hara k. Nihon Rinsho. 2002 Jul;60 Suppl 7:477-86. Nihon Rinsho. 2002. PMID: 12238087 Review. Japanese. No abstract available.
Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.
Vasseur F, Helbecque N, Dina C, Lobbens S, Delannoy V, Gaget S, Boutin P, Vaxillaire M, Leprêtre F, Dupont S, Hara K, Clément K, Bihain B, Kadowaki T, Froguel P. Vasseur F, et al. Among authors: hara k. Hum Mol Genet. 2002 Oct 1;11(21):2607-14. doi: 10.1093/hmg/11.21.2607. Hum Mol Genet. 2002. PMID: 12354786
[Genomics of type 2 diabetes].
Hara K, Kadowaki T. Hara K, et al. Nihon Rinsho. 2002 Aug;60 Suppl 8:283-9. Nihon Rinsho. 2002. PMID: 12355760 Review. Japanese. No abstract available.
[The role of PPARgamma in the onset of type 2 diabetes].
Hara K, Yamauchi T, Kubota N, Tobe K, Yamazaki T, Nagai R, Kadowaki T. Hara K, et al. Nihon Yakurigaku Zasshi. 2003 Oct;122(4):317-24. doi: 10.1254/fpj.122.317. Nihon Yakurigaku Zasshi. 2003. PMID: 14501167 Review. Japanese.
Molecular mechanism of insulin resistance and obesity.
Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R. Kadowaki T, et al. Among authors: hara k. Exp Biol Med (Maywood). 2003 Nov;228(10):1111-7. doi: 10.1177/153537020322801003. Exp Biol Med (Maywood). 2003. PMID: 14610248 Review.
4,239 results