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Page 1
Syntheses of Gliocladin C and Related Alkaloids.
Hodges TR, Benjamin NM, Martin SF. Hodges TR, et al. Org Lett. 2017 May 5;19(9):2254-2257. doi: 10.1021/acs.orglett.7b00735. Epub 2017 Apr 17. Org Lett. 2017. PMID: 28413880
High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model.
Mondal S, Hegarty E, Sahn JJ, Scott LL, Gökçe SK, Martin C, Ghorashian N, Satarasinghe PN, Iyer S, Sae-Lee W, Hodges TR, Pierce JT, Martin SF, Ben-Yakar A. Mondal S, et al. Among authors: hodges tr. ACS Chem Neurosci. 2018 May 16;9(5):1014-1026. doi: 10.1021/acschemneuro.7b00428. Epub 2018 Feb 23. ACS Chem Neurosci. 2018. PMID: 29426225 Free PMC article.
Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors.
Scott LL, Sahn JJ, Ferragud A, Yen RC, Satarasinghe PN, Wood MD, Hodges TR, Shi T, Prakash BA, Friese KM, Shen A, Sabino V, Pierce JT, Martin SF. Scott LL, et al. Among authors: hodges tr. Neuropsychopharmacology. 2018 Aug;43(9):1867-1875. doi: 10.1038/s41386-018-0067-z. Epub 2018 Apr 20. Neuropsychopharmacology. 2018. PMID: 29728649 Free PMC article.
σ2R/TMEM97 in retinal ganglion cell degeneration.
Wang H, Peng Z, Li Y, Sahn JJ, Hodges TR, Chou TH, Liu Q, Zhou X, Jiao S, Porciatti V, Liebl DJ, Martin SF, Wen R. Wang H, et al. Among authors: hodges tr. Sci Rep. 2022 Dec 1;12(1):20753. doi: 10.1038/s41598-022-24537-3. Sci Rep. 2022. PMID: 36456686 Free PMC article.
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
Abbott JR, Hodges TR, Daniels RN, Patel PA, Kennedy JP, Howes JE, Akan DT, Burns MC, Sai J, Sobolik T, Beesetty Y, Lee T, Rossanese OW, Phan J, Waterson AG, Fesik SW. Abbott JR, et al. Among authors: hodges tr. J Med Chem. 2018 Jul 26;61(14):6002-6017. doi: 10.1021/acs.jmedchem.8b00360. Epub 2018 Jul 11. J Med Chem. 2018. PMID: 29856609
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.
Hodges TR, Abbott JR, Little AJ, Sarkar D, Salovich JM, Howes JE, Akan DT, Sai J, Arnold AL, Browning C, Burns MC, Sobolik T, Sun Q, Beesetty Y, Coker JA, Scharn D, Stadtmueller H, Rossanese OW, Phan J, Waterson AG, McConnell DB, Fesik SW. Hodges TR, et al. J Med Chem. 2018 Oct 11;61(19):8875-8894. doi: 10.1021/acs.jmedchem.8b01108. Epub 2018 Sep 28. J Med Chem. 2018. PMID: 30205005 Free PMC article.
45 results