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973 results

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Page 1
Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy.
Steelman LS, Fitzgerald T, Lertpiriyapong K, Cocco L, Follo MY, Martelli AM, Neri LM, Marmiroli S, Libra M, Candido S, Nicoletti F, Scalisi A, Fenga C, Drobot L, Rakus D, Gizak A, Laidler P, Dulinska-Litewka J, Basecke J, Mijatovic S, Maksimovic-Ivanic D, Montalto G, Cervello M, Milella M, Tafuri A, Demidenko Z, Abrams SL, McCubrey JA. Steelman LS, et al. Among authors: nicoletti f. Curr Pharm Des. 2016;22(16):2358-88. doi: 10.2174/1381612822666160304151011. Curr Pharm Des. 2016. PMID: 26947958 Review.
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy.
Misaghian N, Ligresti G, Steelman LS, Bertrand FE, Bäsecke J, Libra M, Nicoletti F, Stivala F, Milella M, Tafuri A, Cervello M, Martelli AM, McCubrey JA. Misaghian N, et al. Among authors: nicoletti f. Leukemia. 2009 Jan;23(1):25-42. doi: 10.1038/leu.2008.246. Epub 2008 Sep 18. Leukemia. 2009. PMID: 18800146 Free PMC article. Review.
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy.
Sokolosky ML, Stadelman KM, Chappell WH, Abrams SL, Martelli AM, Stivala F, Libra M, Nicoletti F, Drobot LB, Franklin RA, Steelman LS, McCubrey JA. Sokolosky ML, et al. Among authors: nicoletti f. Oncotarget. 2011 Jul;2(7):538-50. doi: 10.18632/oncotarget.302. Oncotarget. 2011. PMID: 21730367 Free PMC article.
Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells.
Steelman LS, Navolanic P, Chappell WH, Abrams SL, Wong EW, Martelli AM, Cocco L, Stivala F, Libra M, Nicoletti F, Drobot LB, Franklin RA, McCubrey JA. Steelman LS, et al. Among authors: nicoletti f. Cell Cycle. 2011 Sep 1;10(17):3003-15. doi: 10.4161/cc.10.17.17119. Epub 2011 Sep 1. Cell Cycle. 2011. PMID: 21869603 Free PMC article.
Targeting the cancer initiating cell: the ultimate target for cancer therapy.
McCubrey JA, Steelman LS, Abrams SL, Misaghian N, Chappell WH, Basecke J, Nicoletti F, Libra M, Ligresti G, Stivala F, Maksimovic-Ivanic D, Mijatovic S, Montalto G, Cervello M, Laidler P, Bonati A, Evangelisti C, Cocco L, Martelli AM. McCubrey JA, et al. Among authors: nicoletti f. Curr Pharm Des. 2012;18(13):1784-95. doi: 10.2174/138161212799859701. Curr Pharm Des. 2012. PMID: 22394167 Review.
Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.
Chappell WH, Abrams SL, Franklin RA, LaHair MM, Montalto G, Cervello M, Martelli AM, Nicoletti F, Candido S, Libra M, Polesel J, Talamini R, Milella M, Tafuri A, Steelman LS, McCubrey JA. Chappell WH, et al. Among authors: nicoletti f. Cell Cycle. 2012 Dec 1;11(23):4447-61. doi: 10.4161/cc.22786. Epub 2012 Nov 16. Cell Cycle. 2012. PMID: 23159854 Free PMC article.
Advances in targeting signal transduction pathways.
McCubrey JA, Steelman LS, Chappell WH, Sun L, Davis NM, Abrams SL, Franklin RA, Cocco L, Evangelisti C, Chiarini F, Martelli AM, Libra M, Candido S, Ligresti G, Malaponte G, Mazzarino MC, Fagone P, Donia M, Nicoletti F, Polesel J, Talamini R, Bäsecke J, Mijatovic S, Maksimovic-Ivanic D, Michele M, Tafuri A, Dulińska-Litewka J, Laidler P, D'Assoro AB, Drobot L, Umezawa D, Montalto G, Cervello M, Demidenko ZN. McCubrey JA, et al. Among authors: nicoletti f. Oncotarget. 2012 Dec;3(12):1505-21. doi: 10.18632/oncotarget.802. Oncotarget. 2012. PMID: 23455493 Free PMC article. Review.
Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.
Davis NM, Sokolosky M, Stadelman K, Abrams SL, Libra M, Candido S, Nicoletti F, Polesel J, Maestro R, D'Assoro A, Drobot L, Rakus D, Gizak A, Laidler P, Dulińska-Litewka J, Basecke J, Mijatovic S, Maksimovic-Ivanic D, Montalto G, Cervello M, Fitzgerald TL, Demidenko Z, Martelli AM, Cocco L, Steelman LS, McCubrey JA. Davis NM, et al. Among authors: nicoletti f. Oncotarget. 2014 Jul 15;5(13):4603-50. doi: 10.18632/oncotarget.2209. Oncotarget. 2014. PMID: 25051360 Free PMC article. Review.
The therapeutic potential of mTOR inhibitors in breast cancer.
Steelman LS, Martelli AM, Cocco L, Libra M, Nicoletti F, Abrams SL, McCubrey JA. Steelman LS, et al. Among authors: nicoletti f. Br J Clin Pharmacol. 2016 Nov;82(5):1189-1212. doi: 10.1111/bcp.12958. Epub 2016 May 10. Br J Clin Pharmacol. 2016. PMID: 27059645 Free PMC article. Review.
973 results