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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects.
Talukdar S, Zhou Y, Li D, Rossulek M, Dong J, Somayaji V, Weng Y, Clark R, Lanba A, Owen BM, Brenner MB, Trimmer JK, Gropp KE, Chabot JR, Erion DM, Rolph TP, Goodwin B, Calle RA. Talukdar S, et al. Among authors: gropp ke. Cell Metab. 2016 Mar 8;23(3):427-40. doi: 10.1016/j.cmet.2016.02.001. Cell Metab. 2016. PMID: 26959184 Free article. Clinical Trial.
Once-weekly administration of a long-acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non-human primates.
Kim AM, Somayaji VR, Dong JQ, Rolph TP, Weng Y, Chabot JR, Gropp KE, Talukdar S, Calle RA. Kim AM, et al. Among authors: gropp ke. Diabetes Obes Metab. 2017 Dec;19(12):1762-1772. doi: 10.1111/dom.13023. Epub 2017 Jul 21. Diabetes Obes Metab. 2017. PMID: 28573777 Clinical Trial.
Effects on Cancellous Bone in the Metaphysis.
Gropp KE. Gropp KE. Toxicol Pathol. 2017 Oct;45(7):876-878. doi: 10.1177/0192623317735787. Epub 2017 Oct 15. Toxicol Pathol. 2017. PMID: 29034768
Skeletal Muscle Toolbox.
Gropp KE. Gropp KE. Toxicol Pathol. 2017 Oct;45(7):939-942. doi: 10.1177/0192623317735794. Epub 2017 Oct 15. Toxicol Pathol. 2017. PMID: 29034769
17 results