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Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.
Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC. Pappas CT, et al. Among authors: gregorio cc. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13573-8. doi: 10.1073/pnas.1508273112. Epub 2015 Oct 20. Proc Natl Acad Sci U S A. 2015. PMID: 26487682 Free PMC article.
Overview of the Muscle Cytoskeleton.
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC. Henderson CA, et al. Among authors: gregorio cc. Compr Physiol. 2017 Jun 18;7(3):891-944. doi: 10.1002/cphy.c160033. Compr Physiol. 2017. PMID: 28640448 Free PMC article. Review.
Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy.
Ahrens-Nicklas RC, Pappas CT, Farman GP, Mayfield RM, Larrinaga TM, Medne L, Ritter A, Krantz ID, Murali C, Lin KY, Berger JH, Yum SW, Carreon CK, Gregorio CC. Ahrens-Nicklas RC, et al. Among authors: gregorio cc. Sci Adv. 2019 Sep 4;5(9):eaax2066. doi: 10.1126/sciadv.aax2066. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31517052 Free PMC article.
In vivo elongation of thin filaments results in heart failure.
Mi-Mi L, Farman GP, Mayfield RM, Strom J, Chu M, Pappas CT, Gregorio CC. Mi-Mi L, et al. Among authors: gregorio cc. PLoS One. 2020 Jan 3;15(1):e0226138. doi: 10.1371/journal.pone.0226138. eCollection 2020. PLoS One. 2020. PMID: 31899774 Free PMC article.
Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells.
Iwanski J, Kazmouz SG, Li S, Stansfield B, Salem TT, Perez-Miller S, Kazui T, Jena L, Uhrlaub JL, Lick S, Nikolich-Žugich J, Konhilas JP, Gregorio CC, Khanna M, Campos SK, Churko JM. Iwanski J, et al. Among authors: gregorio cc. Stem Cell Reports. 2021 Oct 12;16(10):2459-2472. doi: 10.1016/j.stemcr.2021.08.018. Epub 2021 Sep 1. Stem Cell Reports. 2021. PMID: 34525378 Free PMC article.
104 results