The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage.
Wikström K, Juhas M, Sjölander A.
Wikström K, et al. Among authors: sjolander a.
Biochem J. 2003 Apr 1;371(Pt 1):115-24. doi: 10.1042/BJ20021669.
Biochem J. 2003.
PMID: 12482325
Free PMC article.
We have shown in a previous study that leukotriene D(4) (LTD(4)) signalling increases cell survival and proliferation in intestinal epithelial cells [Ohd, Wikstrom and Sjolander (2000) Gastroenterology 119, 1007-1018]. ...However, inhibition of COX-2 caused cleavage …
We have shown in a previous study that leukotriene D(4) (LTD(4)) signalling increases cell survival and proliferation in intestinal e …