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A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.
Liu C, Zhou D, Dijokaite-Guraliuc A, Supasa P, Duyvesteyn HME, Ginn HM, Selvaraj M, Mentzer AJ, Das R, de Silva TI, Ritter TG, Plowright M, Newman TAH, Stafford L, Kronsteiner B, Temperton N, Lui Y, Fellermeyer M, Goulder P, Klenerman P, Dunachie SJ, Barton MI, Kutuzov MA, Dushek O; OPTIC Consortium; Fry EE, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR. Liu C, et al. Among authors: goulder p. Cell Rep Med. 2024 May 21;5(5):101553. doi: 10.1016/j.xcrm.2024.101553. Epub 2024 May 8. Cell Rep Med. 2024. PMID: 38723626
Prevalence of resistance-associated viral variants to the HIV-specific broadly neutralising antibody 10-1074 in a UK bNAb-naïve population.
Zacharopoulou P, Lee M, Oliveira T, Thornhill J, Robinson N, Brown H, Kinloch S, Goulder P, Fox J, Fidler S, Ansari MA, Frater J. Zacharopoulou P, et al. Among authors: goulder p. Front Immunol. 2024 Mar 18;15:1352123. doi: 10.3389/fimmu.2024.1352123. eCollection 2024. Front Immunol. 2024. PMID: 38562938 Free PMC article.
Gonadal androgens are associated with decreased type I interferon production by plasmacytoid dendritic cells and increased IgG titres to BNT162b2 following co-vaccination with live attenuated influenza vaccine in adolescents.
Sampson OL, Jay C, Adland E, Csala A, Lim N, Ebbrecht SM, Gilligan LC, Taylor AE, George SS, Longet S, Jones LC, Barnes E, Frater J, Klenerman P, Dunachie S, Carrol M, Hawley J, Arlt W, Groll A, Goulder P. Sampson OL, et al. Among authors: goulder p. Front Immunol. 2024 Feb 28;15:1329805. doi: 10.3389/fimmu.2024.1329805. eCollection 2024. Front Immunol. 2024. PMID: 38481993 Free PMC article.
Age- and sex-specific differences in immune responses to BNT162b2 COVID-19 and live-attenuated influenza vaccines in UK adolescents.
Jay C, Adland E, Csala A, Lim N, Longet S, Ogbe A, Ratcliff J, Sampson O, Thompson CP, Turtle L, Barnes E, Dunachie S, Klenerman P, Carroll M, Goulder P. Jay C, et al. Among authors: goulder p. Front Immunol. 2023 Oct 6;14:1248630. doi: 10.3389/fimmu.2023.1248630. eCollection 2023. Front Immunol. 2023. PMID: 37942333 Free PMC article.
Cellular immunity to SARS-CoV-2 following intrafamilial exposure in seronegative family members.
Jay C, Adland E, Csala A, Dold C, Edmans M, Hackstein CP, Jamsen A, Lim N, Longet S, Ogbe A, Sampson O, Skelly D, Spiller OB, Stafford L, Thompson CP, Turtle L, Barnes E, Dunachie S, Carroll M, Klenerman P, Conlon C, Goulder P, Jones LC. Jay C, et al. Among authors: goulder p. Front Immunol. 2023 Aug 29;14:1248658. doi: 10.3389/fimmu.2023.1248658. eCollection 2023. Front Immunol. 2023. PMID: 37711627 Free PMC article.
Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile.
Nguyen AN, Plotkin AL, Odumade OA, De Armas L, Pahwa S, Morrocchi E, Cotugno N, Rossi P, Foster C, Domínguez-Rodríguez S, Tagarro A, Syphurs C, Diray-Arce J, Fatou B, Ozonoff A, Levy O, Palma P, Smolen KK; on the behalf of the EPIICAL Consortium. Nguyen AN, et al. Pediatr Res. 2023 Nov;94(5):1667-1674. doi: 10.1038/s41390-023-02669-0. Epub 2023 Jun 13. Pediatr Res. 2023. PMID: 37308683
Evaluation of QuantiFERON SARS-CoV-2 interferon-γ release assay following SARS-CoV-2 infection and vaccination.
Johnson SA, Phillips E, Adele S, Longet S, Malone T, Mason C, Stafford L, Jamsen A, Gardiner S, Deeks A, Neo J, Blurton EJ, White J, Ali M, Kronsteiner B, Wilson JD, Skelly DT, Jeffery K, Conlon CP, Goulder P, Consortium P, Carroll M, Barnes E, Klenerman P, Dunachie SJ. Johnson SA, et al. Among authors: goulder p. Clin Exp Immunol. 2023 Jun 5;212(3):249-261. doi: 10.1093/cei/uxad027. Clin Exp Immunol. 2023. PMID: 36807499 Free PMC article.
315 results