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Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke.
Seppälä I, Kleber ME, Bevan S, Lyytikäinen LP, Oksala N, Hernesniemi JA, Mäkelä KM, Rothwell PM, Sudlow C, Dichgans M, Mononen N, Vlachopoulou E, Sinisalo J, Delgado GE, Laaksonen R, Koskinen T, Scharnagl H, Kähönen M, Markus HS, März W, Lehtimäki T. Seppälä I, et al. Sci Rep. 2016 Mar 17;6:23207. doi: 10.1038/srep23207. Sci Rep. 2016. PMID: 26984639 Free PMC article.
Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events.
Mäkelä KM, Traylor M, Oksala N, Kleber ME, Seppälä I, Lyytikäinen LP, Hernesniemi JA, Kähönen M, Bevan S, Rothwell PM, Sudlow C, Dichgans M; Wellcome Trust Case Control Consortium 2 (WTCCC2); Delgado G, Grammer TB, Scharnagl H, Markus HS, März W, Lehtimäki T. Mäkelä KM, et al. Among authors: seppala i. Atherosclerosis. 2014 May;234(1):214-7. doi: 10.1016/j.atherosclerosis.2014.03.002. Epub 2014 Mar 14. Atherosclerosis. 2014. PMID: 24681816
Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque.
Fan YM, Hernesniemi J, Oksala N, Levula M, Raitoharju E, Collings A, Hutri-Kähönen N, Juonala M, Marniemi J, Lyytikäinen LP, Seppälä I, Mennander A, Tarkka M, Kangas AJ, Soininen P, Salenius JP, Klopp N, Illig T, Laitinen T, Ala-Korpela M, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Fan YM, et al. Among authors: seppala i. Sci Rep. 2014 Apr 11;4:4650. doi: 10.1038/srep04650. Sci Rep. 2014. PMID: 24722012 Free PMC article.
Predicting sudden cardiac death using common genetic risk variants for coronary artery disease.
Hernesniemi JA, Lyytikäinen LP, Oksala N, Seppälä I, Kleber ME, Mononen N, März W, Mikkelsson J, Pessi T, Louhelainen AM, Martiskainen M, Nikus K, Klopp N, Waldenberger M, Illig T, Kähönen M, Laaksonen R, Karhunen PJ, Lehtimäki T. Hernesniemi JA, et al. Among authors: seppala i. Eur Heart J. 2015 Jul 7;36(26):1669-75. doi: 10.1093/eurheartj/ehv106. Epub 2015 Apr 23. Eur Heart J. 2015. PMID: 25908775
Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study.
Taipale T, Seppälä I, Raitoharju E, Mononen N, Lyytikäinen LP, Illig T, Waldenberger M, Juonala M, Hutri-Kähönen N, Oksala N, Kähönen M, Raitakari O, Lehtimäki T. Taipale T, et al. Among authors: seppala i. Sci Rep. 2018 Jul 9;8(1):10358. doi: 10.1038/s41598-018-28563-y. Sci Rep. 2018. PMID: 29985430 Free PMC article.
Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts.
Laaksonen J, Mishra PP, Seppälä I, Lyytikäinen LP, Raitoharju E, Mononen N, Lepistö M, Almusa H, Ellonen P, Hutri-Kähönen N, Juonala M, Raitakari O, Kähönen M, Salonen JT, Lehtimäki T. Laaksonen J, et al. Among authors: seppala i. Sci Rep. 2021 Jan 12;11(1):611. doi: 10.1038/s41598-020-79931-6. Sci Rep. 2021. PMID: 33436758 Free PMC article.
Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.
Mäkelä KM, Seppälä I, Hernesniemi JA, Lyytikäinen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kähönen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjärvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JS, Kähönen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, März W, Lehtimäki T. Mäkelä KM, et al. Among authors: seppala i. Circ Cardiovasc Genet. 2013 Feb;6(1):73-81. doi: 10.1161/CIRCGENETICS.112.964965. Epub 2012 Dec 17. Circ Cardiovasc Genet. 2013. PMID: 23247145
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
Seppälä I, Kleber ME, Lyytikäinen LP, Hernesniemi JA, Mäkelä KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kähönen N, Alfthan G, Viikari JS, Kähonen M, Raitakari OT, März W, Meinitzer A, Lehtimäki T; AtheroRemo Consortium. Seppälä I, et al. Eur Heart J. 2014 Feb;35(8):524-31. doi: 10.1093/eurheartj/eht447. Epub 2013 Oct 24. Eur Heart J. 2014. PMID: 24159190 Free article.
Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism-The Young Finns Study.
Raitoharju E, Seppälä I, Lyytikäinen LP, Viikari J, Ala-Korpela M, Soininen P, Kangas AJ, Waldenberger M, Klopp N, Illig T, Leiviskä J, Loo BM, Oksala N, Kähönen M, Hutri-Kähönen N, Laaksonen R, Raitakari O, Lehtimäki T. Raitoharju E, et al. Among authors: seppala i. Sci Rep. 2016 Dec 5;6:38262. doi: 10.1038/srep38262. Sci Rep. 2016. PMID: 27917915 Free PMC article. Clinical Trial.
Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study.
Sulkava M, Raitoharju E, Levula M, Seppälä I, Lyytikäinen LP, Mennander A, Järvinen O, Zeitlin R, Salenius JP, Illig T, Klopp N, Mononen N, Laaksonen R, Kähönen M, Oksala N, Lehtimäki T. Sulkava M, et al. Among authors: seppala i. Sci Rep. 2017 Jan 27;7:41483. doi: 10.1038/srep41483. Sci Rep. 2017. PMID: 28128285 Free PMC article.
240 results