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Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells.
Lee IS, Carvalho CM, Douvaras P, Ho SM, Hartley BJ, Zuccherato LW, Ladran IG, Siegel AJ, McCarthy S, Malhotra D, Sebat J, Rapoport J, Fossati V, Lupski JR, Levy DL, Brennand KJ. Lee IS, et al. Among authors: brennand kj. NPJ Schizophr. 2015 Jun 24;1:15019-. doi: 10.1038/npjschz.2015.19. NPJ Schizophr. 2015. PMID: 26985448 Free PMC article.
The functional and evolutionary impacts of human-specific deletions in conserved elements.
Xue JR, Mackay-Smith A, Mouri K, Garcia MF, Dong MX, Akers JF, Noble M, Li X; Zoonomia Consortium†; Lindblad-Toh K, Karlsson EK, Noonan JP, Capellini TD, Brennand KJ, Tewhey R, Sabeti PC, Reilly SK. Xue JR, et al. Among authors: brennand kj. Science. 2023 Apr 28;380(6643):eabn2253. doi: 10.1126/science.abn2253. Epub 2023 Apr 28. Science. 2023. PMID: 37104592 Free PMC article.
Modelling schizophrenia using human induced pluripotent stem cells.
Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH. Brennand KJ, et al. Nature. 2011 May 12;473(7346):221-5. doi: 10.1038/nature09915. Epub 2011 Apr 13. Nature. 2011. PMID: 21490598 Free PMC article.
Neural stem and progenitor cells in health and disease.
Ladran I, Tran N, Topol A, Brennand KJ. Ladran I, et al. Among authors: brennand kj. Wiley Interdiscip Rev Syst Biol Med. 2013 Nov-Dec;5(6):701-15. doi: 10.1002/wsbm.1239. Epub 2013 Sep 20. Wiley Interdiscip Rev Syst Biol Med. 2013. PMID: 24068527 Free PMC article. Review.
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.
Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, Fang G, Zhang B, Yates JR 3rd, Gage FH. Brennand K, et al. Mol Psychiatry. 2015 Mar;20(3):361-8. doi: 10.1038/mp.2014.22. Epub 2014 Apr 1. Mol Psychiatry. 2015. PMID: 24686136 Free PMC article.
Dopaminergic differentiation of schizophrenia hiPSCs.
Hartley BJ, Tran N, Ladran I, Reggio K, Brennand KJ. Hartley BJ, et al. Among authors: brennand kj. Mol Psychiatry. 2015 May;20(5):549-50. doi: 10.1038/mp.2014.194. Epub 2015 Jan 27. Mol Psychiatry. 2015. PMID: 25623947 Free PMC article. No abstract available.
Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.
Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, Aronow B, Fang G, Zhang B, Cotter D, Brennand KJ. Topol A, et al. Among authors: brennand kj. Transl Psychiatry. 2015 Oct 20;5(10):e662. doi: 10.1038/tp.2015.118. Transl Psychiatry. 2015. PMID: 26485546 Free PMC article.
150 results