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Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells.
NPJ Schizophr. 2015 Jun 24;1:15019-. doi: 10.1038/npjschz.2015.19.
NPJ Schizophr. 2015.
PMID: 26985448
Free PMC article.
Neural stem and progenitor cells in health and disease.
Ladran I, Tran N, Topol A, Brennand KJ.
Ladran I, et al.
Wiley Interdiscip Rev Syst Biol Med. 2013 Nov-Dec;5(6):701-15. doi: 10.1002/wsbm.1239. Epub 2013 Sep 20.
Wiley Interdiscip Rev Syst Biol Med. 2013.
PMID: 24068527
Free PMC article.
Review.
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Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.
Hoffman GE, Hartley BJ, Flaherty E, Ladran I, Gochman P, Ruderfer DM, Stahl EA, Rapoport J, Sklar P, Brennand KJ.
Hoffman GE, et al.
Nat Commun. 2017 Dec 20;8(1):2225. doi: 10.1038/s41467-017-02330-5.
Nat Commun. 2017.
PMID: 29263384
Free PMC article.
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Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons.
Tran NN, Ladran IG, Brennand KJ.
Tran NN, et al. Among authors: ladran ig.
Schizophr Bull. 2013 Jan;39(1):4-10. doi: 10.1093/schbul/sbs127. Epub 2012 Nov 19.
Schizophr Bull. 2013.
PMID: 23172000
Free PMC article.
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Dopaminergic differentiation of schizophrenia hiPSCs.
Hartley BJ, Tran N, Ladran I, Reggio K, Brennand KJ.
Hartley BJ, et al.
Mol Psychiatry. 2015 May;20(5):549-50. doi: 10.1038/mp.2014.194. Epub 2015 Jan 27.
Mol Psychiatry. 2015.
PMID: 25623947
Free PMC article.
No abstract available.
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Neuronal impact of patient-specific aberrant NRXN1α splicing.
Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJM, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, Halpern M, Deikus G, Shah H, Fitzgerald M, Ladran I, Gochman P, Rapoport J, Tsankova NM, McCullumsmith R, Hoffman GE, Sebra R, Fang G, Brennand KJ.
Flaherty E, et al.
Nat Genet. 2019 Dec;51(12):1679-1690. doi: 10.1038/s41588-019-0539-z. Epub 2019 Nov 29.
Nat Genet. 2019.
PMID: 31784728
Free PMC article.
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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.
Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, Fang G, Zhang B, Yates JR 3rd, Gage FH.
Brennand K, et al.
Mol Psychiatry. 2015 Mar;20(3):361-8. doi: 10.1038/mp.2014.22. Epub 2014 Apr 1.
Mol Psychiatry. 2015.
PMID: 24686136
Free PMC article.
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