Hagemann T - Search Results

1

Loss of P53 Function Activates JAK2-STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival.

Wörmann SM, Song L, Ai J, Diakopoulos KN, Kurkowski MU, Görgülü K, Ruess D, Campbell A, Doglioni C, Jodrell D, Neesse A, Demir IE, Karpathaki AP, Barenboim M, Hagemann T, Rose-John S, Sansom O, Schmid RM, Protti MP, Lesina M, Algül H. Wörmann SM, et al. Among authors: hagemann t. Gastroenterology. 2016 Jul;151(1):180-193.e12. doi: 10.1053/j.gastro.2016.03.010. Epub 2016 Mar 19. Gastroenterology. 2016. PMID: 27003603

2

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.

Maniati E, Bossard M, Cook N, Candido JB, Emami-Shahri N, Nedospasov SA, Balkwill FR, Tuveson DA, Hagemann T. Maniati E, et al. Among authors: hagemann t. J Clin Invest. 2011 Dec;121(12):4685-99. doi: 10.1172/JCI45797. Epub 2011 Nov 7. J Clin Invest. 2011. PMID: 22056382 Free PMC article.

3

Inflammatory cytokines in human pancreatic cancer.

Roshani R, McCarthy F, Hagemann T. Roshani R, et al. Among authors: hagemann t. Cancer Lett. 2014 Apr 10;345(2):157-63. doi: 10.1016/j.canlet.2013.07.014. Epub 2013 Jul 20. Cancer Lett. 2014. PMID: 23879960 Review.

4

Resistance to the tyrosine kinase inhibitor axitinib is associated with increased glucose metabolism in pancreatic adenocarcinoma.

Hudson CD, Hagemann T, Mather SJ, Avril N. Hudson CD, et al. Among authors: hagemann t. Cell Death Dis. 2014 Apr 10;5(4):e1160. doi: 10.1038/cddis.2014.125. Cell Death Dis. 2014. PMID: 24722285 Free PMC article.

5

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.

Wong PP, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford MR, Scudamore CL, Cereser B, Crnogorac-Jurcevic T, McDonald S, Elia G, Hagemann T, Kocher HM, Hodivala-Dilke KM. Wong PP, et al. Among authors: hagemann t. Cancer Cell. 2015 Jan 12;27(1):123-37. doi: 10.1016/j.ccell.2014.10.015. Cancer Cell. 2015. PMID: 25584895 Free article.

6

Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB.

Hagemann T, Biswas SK, Lawrence T, Sica A, Lewis CE. Hagemann T, et al. Blood. 2009 Apr 2;113(14):3139-46. doi: 10.1182/blood-2008-12-172825. Epub 2009 Jan 26. Blood. 2009. PMID: 19171876 Free PMC article. Review.

7

The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy in Pancreatic Cancer Models by Altering Ribonucleotide Reductase Subunit-1 (RRM1).

Vena F, Li Causi E, Rodriguez-Justo M, Goodstal S, Hagemann T, Hartley JA, Hochhauser D. Vena F, et al. Among authors: hagemann t. Clin Cancer Res. 2015 Dec 15;21(24):5563-77. doi: 10.1158/1078-0432.CCR-15-0485. Epub 2015 Jul 30. Clin Cancer Res. 2015. PMID: 26228206

8

A role for endothelin-2 and its receptors in breast tumor cell invasion.

Grimshaw MJ, Hagemann T, Ayhan A, Gillett CE, Binder C, Balkwill FR. Grimshaw MJ, et al. Among authors: hagemann t. Cancer Res. 2004 Apr 1;64(7):2461-8. doi: 10.1158/0008-5472.can-03-1069. Cancer Res. 2004. PMID: 15059899

9

ADAM8 as a drug target in pancreatic cancer.

Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW. Schlomann U, et al. Among authors: hagemann t. Nat Commun. 2015 Jan 28;6:6175. doi: 10.1038/ncomms7175. Nat Commun. 2015. PMID: 25629724 Free PMC article.

10

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.

Charles KA, Kulbe H, Soper R, Escorcio-Correia M, Lawrence T, Schultheis A, Chakravarty P, Thompson RG, Kollias G, Smyth JF, Balkwill FR, Hagemann T. Charles KA, et al. Among authors: hagemann t. J Clin Invest. 2009 Oct;119(10):3011-23. doi: 10.1172/JCI39065. Epub 2009 Sep 8. J Clin Invest. 2009. PMID: 19741298 Free PMC article.

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