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Soyasaponin Bb inhibits the recruitment of toll-like receptor 4 (TLR4) into lipid rafts and its signaling pathway by suppressing the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent generation of reactive oxygen species.
Zhang Y, Chen F, Chen J, Huang S, Chen J, Huang J, Li N, Sun S, Chu X, Zha L. Zhang Y, et al. Among authors: huang s, huang j. Mol Nutr Food Res. 2016 Jul;60(7):1532-43. doi: 10.1002/mnfr.201600015. Epub 2016 Apr 21. Mol Nutr Food Res. 2016. PMID: 27005845
Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation.
Zhou Y, Bastian IN, Long MD, Dow M, Li W, Liu T, Ngu RK, Antonucci L, Huang JY, Phung QT, Zhao XH, Banerjee S, Lin XJ, Wang H, Dang B, Choi S, Karin D, Su H, Ellisman MH, Jamieson C, Bosenberg M, Cheng Z, Haybaeck J, Kenner L, Fisch KM, Bourgon R, Hernandez G, Lill JR, Liu S, Carter H, Mellman I, Karin M, Shalapour S. Zhou Y, et al. Among authors: huang jy. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2025840118. doi: 10.1073/pnas.2025840118. Proc Natl Acad Sci U S A. 2021. PMID: 33602823 Free PMC article.
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