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247 results

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Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.
Zhou H, Hoek M, Yi P, Rohm RJ, Mahsut A, Brown P, Saunders J, Chmielowski RA, Ren N, Shuster D, Southwick K, Ayanoglu G, Gorman D, Laface D, Santino S, Conway J, Liu Z, Cully D, Cleary M, Roddy TP, Blom D. Zhou H, et al. Among authors: blom d. Rapid Commun Mass Spectrom. 2013 Dec 15;27(23):2639-47. doi: 10.1002/rcm.6734. Rapid Commun Mass Spectrom. 2013. PMID: 24591025
Anthranilic acid replacements in a niacin receptor agonist.
Schmidt D, Smenton A, Raghavan S, Shen H, Ding FX, Carballo-Jane E, Luell S, Ciecko T, Holt TG, Wolff M, Taggart A, Wilsie L, Krsmanovic M, Ren N, Blom D, Cheng K, McCann PE, Waters MG, Tata J, Colletti S. Schmidt D, et al. Among authors: blom d. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3426-30. doi: 10.1016/j.bmcl.2010.04.001. Epub 2010 Apr 8. Bioorg Med Chem Lett. 2010. PMID: 20444602
Pyrazole acids as niacin receptor agonists for the treatment of dyslipidemia.
Schmidt D, Smenton A, Raghavan S, Carballo-Jane E, Lubell S, Ciecko T, Holt TG, Wolff M, Taggart A, Wilsie L, Krsmanovic M, Ren N, Blom D, Cheng K, McCann PE, Gerard Waters M, Tata J, Colletti S. Schmidt D, et al. Among authors: blom d. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4768-72. doi: 10.1016/j.bmcl.2009.06.054. Epub 2009 Jun 17. Bioorg Med Chem Lett. 2009. PMID: 19592242
Altered lipoprotein metabolism in P2Y(13) knockout mice.
Blom D, Yamin TT, Champy MF, Selloum M, Bedu E, Carballo-Jane E, Gerckens L, Luell S, Meurer R, Chin J, Mudgett J, Puig O. Blom D, et al. Biochim Biophys Acta. 2010 Dec;1801(12):1349-60. doi: 10.1016/j.bbalip.2010.08.013. Epub 2010 Sep 15. Biochim Biophys Acta. 2010. PMID: 20817122
An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.
Zhang L, McCabe T, Condra JH, Ni YG, Peterson LB, Wang W, Strack AM, Wang F, Pandit S, Hammond H, Wood D, Lewis D, Rosa R, Mendoza V, Cumiskey AM, Johns DG, Hansen BC, Shen X, Geoghagen N, Jensen K, Zhu L, Wietecha K, Wisniewski D, Huang L, Zhao JZ, Ernst R, Hampton R, Haytko P, Ansbro F, Chilewski S, Chin J, Mitnaul LJ, Pellacani A, Sparrow CP, An Z, Strohl W, Hubbard B, Plump AS, Blom D, Sitlani A. Zhang L, et al. Among authors: blom d. Int J Biol Sci. 2012;8(3):310-27. doi: 10.7150/ijbs.3524. Epub 2012 Feb 9. Int J Biol Sci. 2012. PMID: 22355267 Free PMC article.
Reduced body weight in male Tspan8-deficient mice.
Champy MF, Le Voci L, Selloum M, Peterson LB, Cumiskey AM, Blom D. Champy MF, et al. Among authors: blom d. Int J Obes (Lond). 2011 Apr;35(4):605-17. doi: 10.1038/ijo.2010.165. Epub 2010 Aug 24. Int J Obes (Lond). 2011. PMID: 20733586
Cardiovascular outcomes in patients with homozygous familial hypercholesterolaemia on lipoprotein apheresis initiated during childhood: long-term follow-up of an international cohort from two registries.
Reijman MD, Tromp TR, Hutten BA, Hovingh GK, Blom DJ, Catapano AL, Cuchel M, Dann EJ, Gallo A, Hudgins LC, Raal FJ, Ray KK, Sadiq F, Soran H, Groothoff JW, Wiegman A, Kusters DM; Homozygous Familial Hypercholesterolaemia International Clinical Collaborators (HICC); Children with Homozygous Hypercholesterolemia on Lipoprotein Apheresis: an International Registry (CHAIN) consortia. Reijman MD, et al. Among authors: blom dj. Lancet Child Adolesc Health. 2024 May 14:S2352-4642(24)00073-7. doi: 10.1016/S2352-4642(24)00073-7. Online ahead of print. Lancet Child Adolesc Health. 2024. PMID: 38759658
Management of hyperlipidaemia.
Marais AD, Blom DJ, Raal FJ. Marais AD, et al. Among authors: blom dj. S Afr Med J. 2024 Mar 18;114(3):e1016. doi: 10.7196/SAMJ.2024.v114i3.1964. S Afr Med J. 2024. PMID: 38525564 Free article. No abstract available.
247 results