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Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library.
Comb Chem High Throughput Screen. 2016;19(4):262-74. doi: 10.2174/1386207319666160324123844.
Comb Chem High Throughput Screen. 2016.
PMID: 27009891
Free PMC article.
The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate.
Mitchell DA, Hamel LD, Ishizuka K, Mitchell G, Schaefer LM, Deschenes RJ.
Mitchell DA, et al. Among authors: hamel ld.
J Biol Chem. 2012 Oct 5;287(41):34337-48. doi: 10.1074/jbc.M112.379297. Epub 2012 Aug 16.
J Biol Chem. 2012.
PMID: 22904317
Free PMC article.
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A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening.
Hamel LD, Deschenes RJ, Mitchell DA.
Hamel LD, et al.
Anal Biochem. 2014 Sep 1;460:1-8. doi: 10.1016/j.ab.2014.05.013. Epub 2014 May 27.
Anal Biochem. 2014.
PMID: 24878334
Free PMC article.
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Mutations in the X-linked intellectual disability gene, zDHHC9, alter autopalmitoylation activity by distinct mechanisms.
Mitchell DA, Hamel LD, Reddy KD, Farh L, Rettew LM, Sanchez PR, Deschenes RJ.
Mitchell DA, et al. Among authors: hamel ld.
J Biol Chem. 2014 Jun 27;289(26):18582-92. doi: 10.1074/jbc.M114.567420. Epub 2014 May 8.
J Biol Chem. 2014.
PMID: 24811172
Free PMC article.
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Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
Anderson LE, Dring AM, Hamel LD, Stoner MA.
Anderson LE, et al. Among authors: hamel ld.
Toxicol Lett. 2011 Apr 25;202(2):148-54. doi: 10.1016/j.toxlet.2011.02.004. Epub 2011 Feb 18.
Toxicol Lett. 2011.
PMID: 21315811
Free PMC article.
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