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Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B. Castillo SD, et al. Among authors: graupera m. Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982. Sci Transl Med. 2016. PMID: 27030595 Free PMC article.
The emerging mechanisms of isoform-specific PI3K signalling.
Vanhaesebroeck B, Guillermet-Guibert J, Graupera M, Bilanges B. Vanhaesebroeck B, et al. Among authors: graupera m. Nat Rev Mol Cell Biol. 2010 May;11(5):329-41. doi: 10.1038/nrm2882. Epub 2010 Apr 9. Nat Rev Mol Cell Biol. 2010. PMID: 20379207 Review.
Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.
Guillermet-Guibert J, Smith LB, Halet G, Whitehead MA, Pearce W, Rebourcet D, León K, Crépieux P, Nock G, Strömstedt M, Enerback M, Chelala C, Graupera M, Carroll J, Cosulich S, Saunders PT, Huhtaniemi I, Vanhaesebroeck B. Guillermet-Guibert J, et al. Among authors: graupera m. PLoS Genet. 2015 Jul 1;11(7):e1005304. doi: 10.1371/journal.pgen.1005304. eCollection 2015 Jul. PLoS Genet. 2015. PMID: 26132308 Free PMC article.
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, Pandolfi PP, Bigas A, Carracedo A, Gerhardt H, Graupera M. Serra H, et al. Among authors: graupera m. Nat Commun. 2015 Jul 31;6:7935. doi: 10.1038/ncomms8935. Nat Commun. 2015. PMID: 26228240 Free PMC article.
PI3K at the crossroads of tumor angiogenesis signaling pathways.
Soler A, Angulo-Urarte A, Graupera M. Soler A, et al. Among authors: graupera m. Mol Cell Oncol. 2015 Feb 26;2(2):e975624. doi: 10.4161/23723556.2014.975624. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308431 Free PMC article. Review.
73 results