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High-level transgene expression by homologous recombination-mediated gene transfer.
Grandjean M, Girod PA, Calabrese D, Kostyrko K, Wicht M, Yerly F, Mazza C, Beckmann JS, Martinet D, Mermod N. Grandjean M, et al. Among authors: kostyrko k. Nucleic Acids Res. 2011 Aug;39(15):e104. doi: 10.1093/nar/gkr436. Epub 2011 Jun 7. Nucleic Acids Res. 2011. PMID: 21652640 Free PMC article.
Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response.
Norgard RJ, Budhani P, O'Brien SA, Xia Y, Egan JN, Flynn B, Tagore JR, Seco J, Peet GW, Mikucka A, Wasti R, Chan LC, Hinkel M, Martinez-Morilla S, Pignatelli J, Trapani F, Corse E, Feng D, Kostyrko K, Hofmann MH, Liu K, Kashyap A. Norgard RJ, et al. Among authors: kostyrko k. Cancer Res Commun. 2024 May 10. doi: 10.1158/2767-9764.CRC-24-0172. Online ahead of print. Cancer Res Commun. 2024. PMID: 38727236 Free article.
UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma.
Kostyrko K, Román M, Lee AG, Simpson DR, Dinh PT, Leung SG, Marini KD, Kelly MR, Broyde J, Califano A, Jackson PK, Sweet-Cordero EA. Kostyrko K, et al. Nat Commun. 2023 Jul 5;14(1):3966. doi: 10.1038/s41467-023-39591-2. Nat Commun. 2023. PMID: 37407562 Free PMC article.
Combined KRASG12C and SOS1 inhibition enhances and extends the anti-tumor response in KRASG12C-driven cancers by addressing intrinsic and acquired resistance.
Thatikonda V, Lu H, Jurado S, Kostyrko K, Bristow CA, Bosch K, Feng N, Gao S, Gerlach D, Gmachl M, Lieb S, Jeschko A, Machado AA, Marszalek ED, Mahendra M, Jaeger PA, Sorokin A, Strauss S, Trapani F, Kopetz S, Vellano CP, Petronczki M, Kraut N, Heffernan TP, Marszalek JR, Pearson M, Waizenegger I, Hofmann MH. Thatikonda V, et al. Among authors: kostyrko k. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525210. doi: 10.1101/2023.01.23.525210. bioRxiv. 2023. PMID: 36747713 Free PMC article. Preprint.
16 results