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Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Zimmer S, et al. Among authors: hawxhurst v. Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100. Sci Transl Med. 2016. PMID: 27053774 Free PMC article.
LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.
Tamehiro N, Park MH, Hawxhurst V, Nagpal K, Adams ME, Zannis VI, Golenbock DT, Fitzgerald ML. Tamehiro N, et al. Among authors: hawxhurst v. Biochemistry. 2015 Nov 24;54(46):6931-41. doi: 10.1021/acs.biochem.5b00894. Epub 2015 Nov 9. Biochemistry. 2015. PMID: 26506427 Free PMC article.
High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection.
Lo J, Rosenberg ES, Fitzgerald ML, Bazner SB, Ihenachor EJ, Hawxhurst V, Borkowska AH, Wei J, Zimmerman CO, Burdo TH, Williams KC, Freeman MW, Grinspoon SK. Lo J, et al. Among authors: hawxhurst v. Open Forum Infect Dis. 2014 Dec 16;1(3):ofu108. doi: 10.1093/ofid/ofu108. eCollection 2014 Dec. Open Forum Infect Dis. 2014. PMID: 25734176 Free PMC article.