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Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Zimmer S, et al. Among authors: heneka mt. Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100. Sci Transl Med. 2016. PMID: 27053774 Free PMC article.
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Tamboli IY, et al. Among authors: heneka mt. J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008. J Neurosci. 2008. PMID: 19005074 Free PMC article.
Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, Lütjohann D, Wunderlich P, Walter J. Tamboli IY, et al. Among authors: heneka mt. J Biol Chem. 2010 Nov 26;285(48):37405-14. doi: 10.1074/jbc.M110.149468. Epub 2010 Sep 28. J Biol Chem. 2010. PMID: 20876579 Free PMC article.
Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.
Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Kummer MP, et al. Among authors: heneka mt. J Neurosci. 2014 Jun 25;34(26):8845-54. doi: 10.1523/JNEUROSCI.4027-13.2014. J Neurosci. 2014. PMID: 24966384 Free PMC article.
Innate immunity in Alzheimer's disease.
Heneka MT, Golenbock DT, Latz E. Heneka MT, et al. Nat Immunol. 2015 Mar;16(3):229-36. doi: 10.1038/ni.3102. Nat Immunol. 2015. PMID: 25689443 Review.
Activation of the NLRP3 inflammasome in microglia: the role of ceramide.
Scheiblich H, Schlütter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT. Scheiblich H, et al. Among authors: heneka mt. J Neurochem. 2017 Dec;143(5):534-550. doi: 10.1111/jnc.14225. Epub 2017 Oct 26. J Neurochem. 2017. PMID: 28940479 Free article.
Innate Immunity and Neurodegeneration.
Labzin LI, Heneka MT, Latz E. Labzin LI, et al. Among authors: heneka mt. Annu Rev Med. 2018 Jan 29;69:437-449. doi: 10.1146/annurev-med-050715-104343. Epub 2017 Nov 6. Annu Rev Med. 2018. PMID: 29106805 Review.
308 results