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Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.
Guillem-Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, Grande R, Alberti S, Arena V, Cirillo M, Patrono C, FitzGerald GA, Steinhilber D, Sgambato A, Patrignani P. Guillem-Llobat P, et al. Among authors: patrono c. Oncotarget. 2016 May 31;7(22):32462-77. doi: 10.18632/oncotarget.8655. Oncotarget. 2016. PMID: 27074574 Free PMC article.
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.
Renda G, Tacconelli S, Capone ML, Sacchetta D, Santarelli F, Sciulli MG, Zimarino M, Grana M, D'Amelio E, Zurro M, Price TS, Patrono C, De Caterina R, Patrignani P. Renda G, et al. Among authors: patrono c. Clin Pharmacol Ther. 2006 Sep;80(3):264-74. doi: 10.1016/j.clpt.2006.05.004. Clin Pharmacol Ther. 2006. PMID: 16952493 Clinical Trial.
Aspirin and Cancer.
Patrignani P, Patrono C. Patrignani P, et al. Among authors: patrono c. J Am Coll Cardiol. 2016 Aug 30;68(9):967-76. doi: 10.1016/j.jacc.2016.05.083. J Am Coll Cardiol. 2016. PMID: 27561771 Free article. Review.
Aspirin, platelet inhibition and cancer prevention.
Patrignani P, Patrono C. Patrignani P, et al. Among authors: patrono c. Platelets. 2018 Dec;29(8):779-785. doi: 10.1080/09537104.2018.1492105. Epub 2018 Jul 9. Platelets. 2018. PMID: 29985750 Review.
Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice.
Sacco A, Bruno A, Contursi A, Dovizio M, Tacconelli S, Ricciotti E, Guillem-Llobat P, Salvatore T, Di Francesco L, Fullone R, Ballerini P, Arena V, Alberti S, Liu G, Gong Y, Sgambato A, Patrono C, FitzGerald GA, Yu Y, Patrignani P. Sacco A, et al. Among authors: patrono c. J Pharmacol Exp Ther. 2019 Sep;370(3):416-426. doi: 10.1124/jpet.119.259382. Epub 2019 Jun 27. J Pharmacol Exp Ther. 2019. PMID: 31248980
Effect of Low-dose and Standard-dose Aspirin on PGE2 Biosynthesis Among Individuals with Colorectal Adenomas: A Randomized Clinical Trial.
Drew DA, Schuck MM, Magicheva-Gupta MV, Stewart KO, Gilpin KK, Miller P, Parziale MP, Pond EN, Takacsi-Nagy O, Zerjav DC, Chin SM, Mackinnon Krems J, Meixell D, Joshi AD, Ma W, Colizzo FP, Carolan PJ, Nishioka NS, Staller K, Richter JM, Khalili H, Gala MK, Garber JJ, Chung DC, Yarze JC, Zukerberg L, Petrucci G, Rocca B, Patrono C, Milne GL, Wang M, Chan AT. Drew DA, et al. Among authors: patrono c. Cancer Prev Res (Phila). 2020 Oct;13(10):877-888. doi: 10.1158/1940-6207.CAPR-20-0216. Epub 2020 Jul 27. Cancer Prev Res (Phila). 2020. PMID: 32718943 Free PMC article. Clinical Trial.
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