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Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Oftedal BE, Hellesen A, Erichsen MM, Bratland E, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WA, Sozaeva LS, Zayats T, Haugarvoll K, Orlova EM, Haavik J, Johansson S, Knappskog PM, Løvås K, Wolff AS, Abramson J, Husebye ES. Oftedal BE, et al. Among authors: abramson j. Immunity. 2015 Jun 16;42(6):1185-96. doi: 10.1016/j.immuni.2015.04.021. Immunity. 2015. PMID: 26084028 Free article.
Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shkedy A, Eisenberg-Bord M, Levi B, Delacher M, Goldfarb Y, David E, Weinberger L, Viukov S, Ben-Dor S, Giraud M, Hanna JH, Breiling A, Lyko F, Amit I, Feuerer M, Abramson J. Herzig Y, et al. Among authors: abramson j. Nat Immunol. 2017 Feb;18(2):161-172. doi: 10.1038/ni.3638. Epub 2016 Dec 12. Nat Immunol. 2017. PMID: 27941786
Thymic Epithelial Cells.
Abramson J, Anderson G. Abramson J, et al. Annu Rev Immunol. 2017 Apr 26;35:85-118. doi: 10.1146/annurev-immunol-051116-052320. Epub 2017 Feb 10. Annu Rev Immunol. 2017. PMID: 28226225
Thymic epithelial cell heterogeneity: TEC by TEC.
Kadouri N, Nevo S, Goldfarb Y, Abramson J. Kadouri N, et al. Among authors: abramson j. Nat Rev Immunol. 2020 Apr;20(4):239-253. doi: 10.1038/s41577-019-0238-0. Epub 2019 Dec 5. Nat Rev Immunol. 2020. PMID: 31804611 Review.
Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation.
Goldfarb Y, Givony T, Kadouri N, Dobeš J, Peligero-Cruz C, Zalayat I, Damari G, Dassa B, Ben-Dor S, Gruper Y, Oftedal BE, Bratland E, Erichsen MM, Berger A, Avin A, Nevo S, Haljasorg U, Kuperman Y, Ulman A, Haffner-Krausz R, Porat Z, Atasoy U, Leshkowitz D, Husebye ES, Abramson J. Goldfarb Y, et al. Among authors: abramson j. J Exp Med. 2021 Nov 1;218(11):e20201076. doi: 10.1084/jem.20201076. Epub 2021 Sep 3. J Exp Med. 2021. PMID: 34477806 Free PMC article.
718 results